Epstein-Barr virus in normal pregnant women

K. Sakamoto; J. Greally; R. F. Gilfillan; J. Sexton; V. Barnabei; J. Yetz; T. Bechtold; J. K. Seeley; E. O'Dwyer; D. T. Purtilo

doi:10.1111/j.1600-0897.1982.tb00169.x

Epstein-Barr virus in normal pregnant women

K. Sakamoto
, J. Greally
, R. F. Gilfillan
, J. Sexton
, V. Barnabei
, J. Yetz
, T. Bechtold
, J. K. Seeley
, E. O'Dwyer
, D. T. Purtilo

Department of Obstetrics and Gynecology

University of Massachusetts Medical School

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Acquired immune suppression accompanying normal pregnancy may be associated with reactivation of Epstein-Barr virus (EBV). Pregnant women with reactivated EBV having anti-EA antibodies show high titers of antiviral capsid antigen (VCA) geometric mean titers (GMT) of 522 versus 170 in those lacking anti-early antigen (EA). Among twenty-seven seropositive women at parturition, 17 (63%) had generated antibody to EA, and all 27 (100%) demonstrated significant increases in antibody to VCA (p<0.01). In contrast, antibody titers to cytomegalovirus, herpes hominis, varicella-zoster, and rubella viruses, in the pregnant women were comparable to those found in nonpregnant controls.

Original language	English
Pages (from-to)	217-221
Number of pages	5
Journal	Unknown Journal
Volume	2
Issue number	4
DOIs	https://doi.org/10.1111/j.1600-0897.1982.tb00169.x
State	Published - 1982

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10.1111/j.1600-0897.1982.tb00169.x

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title = "Epstein-Barr virus in normal pregnant women",

abstract = "Acquired immune suppression accompanying normal pregnancy may be associated with reactivation of Epstein-Barr virus (EBV). Pregnant women with reactivated EBV having anti-EA antibodies show high titers of antiviral capsid antigen (VCA) geometric mean titers (GMT) of 522 versus 170 in those lacking anti-early antigen (EA). Among twenty-seven seropositive women at parturition, 17 (63\%) had generated antibody to EA, and all 27 (100\%) demonstrated significant increases in antibody to VCA (p<0.01). In contrast, antibody titers to cytomegalovirus, herpes hominis, varicella-zoster, and rubella viruses, in the pregnant women were comparable to those found in nonpregnant controls.",

author = "K. Sakamoto and J. Greally and Gilfillan, \{R. F.\} and J. Sexton and V. Barnabei and J. Yetz and T. Bechtold and Seeley, \{J. K.\} and E. O'Dwyer and Purtilo, \{D. T.\}",

year = "1982",

doi = "10.1111/j.1600-0897.1982.tb00169.x",

language = "English",

volume = "2",

pages = "217--221",

journal = "Unknown Journal",

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TY - JOUR

T1 - Epstein-Barr virus in normal pregnant women

AU - Sakamoto, K.

AU - Greally, J.

AU - Gilfillan, R. F.

AU - Sexton, J.

AU - Barnabei, V.

AU - Yetz, J.

AU - Bechtold, T.

AU - Seeley, J. K.

AU - O'Dwyer, E.

AU - Purtilo, D. T.

PY - 1982

Y1 - 1982

N2 - Acquired immune suppression accompanying normal pregnancy may be associated with reactivation of Epstein-Barr virus (EBV). Pregnant women with reactivated EBV having anti-EA antibodies show high titers of antiviral capsid antigen (VCA) geometric mean titers (GMT) of 522 versus 170 in those lacking anti-early antigen (EA). Among twenty-seven seropositive women at parturition, 17 (63%) had generated antibody to EA, and all 27 (100%) demonstrated significant increases in antibody to VCA (p<0.01). In contrast, antibody titers to cytomegalovirus, herpes hominis, varicella-zoster, and rubella viruses, in the pregnant women were comparable to those found in nonpregnant controls.

AB - Acquired immune suppression accompanying normal pregnancy may be associated with reactivation of Epstein-Barr virus (EBV). Pregnant women with reactivated EBV having anti-EA antibodies show high titers of antiviral capsid antigen (VCA) geometric mean titers (GMT) of 522 versus 170 in those lacking anti-early antigen (EA). Among twenty-seven seropositive women at parturition, 17 (63%) had generated antibody to EA, and all 27 (100%) demonstrated significant increases in antibody to VCA (p<0.01). In contrast, antibody titers to cytomegalovirus, herpes hominis, varicella-zoster, and rubella viruses, in the pregnant women were comparable to those found in nonpregnant controls.

UR - https://www.scopus.com/pages/publications/0020399775

U2 - 10.1111/j.1600-0897.1982.tb00169.x

DO - 10.1111/j.1600-0897.1982.tb00169.x

M3 - Article

C2 - 6291416

AN - SCOPUS:0020399775

VL - 2

SP - 217

EP - 221

JO - Unknown Journal

JF - Unknown Journal

IS - 4

ER -

Epstein-Barr virus in normal pregnant women

Abstract

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