Epigenetics-based treatment strategies for Alzheimer’s disease

Qing Cao; Wei Wang; Zhen Yan

doi:10.18632/aging.204096

Epigenetics-based treatment strategies for Alzheimer’s disease

Qing Cao
, Wei Wang
, Zhen Yan

Physiology and Biophysics

SUNY Buffalo

Research output: Contribution to journal › Editorial

3 Scopus citations

Abstract

Alzheimer’s disease (AD) is a progressive neuro-degenerative disease characterized by the impairment of cognitive function. While the pathological hallmarks of AD, amyloid plaques and neurofibrillary tangles, have been studied intensively, effective treatment for AD is still lacking. Emerging evidence suggests that gene transcriptional changes due to epigenetic abnormality during aging may play a key role in AD patho-physiology [1].

Original language	English
Pages (from-to)	4193-4194
Number of pages	2
Journal	Aging
Volume	14
Issue number	10
DOIs	https://doi.org/10.18632/aging.204096
State	Published - 2022

Keywords

Alzheimer’s disease
Ehmt
Epigenetics
Histone methylation
Prefrontal cortex

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10.18632/aging.204096

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title = "Epigenetics-based treatment strategies for Alzheimer{\textquoteright}s disease",

abstract = "Alzheimer{\textquoteright}s disease (AD) is a progressive neuro-degenerative disease characterized by the impairment of cognitive function. While the pathological hallmarks of AD, amyloid plaques and neurofibrillary tangles, have been studied intensively, effective treatment for AD is still lacking. Emerging evidence suggests that gene transcriptional changes due to epigenetic abnormality during aging may play a key role in AD patho-physiology [1].",

keywords = "Alzheimer{\textquoteright}s disease, Ehmt, Epigenetics, Histone methylation, Prefrontal cortex",

author = "Qing Cao and Wei Wang and Zhen Yan",

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T1 - Epigenetics-based treatment strategies for Alzheimer’s disease

AU - Cao, Qing

AU - Wang, Wei

AU - Yan, Zhen

N1 - Publisher Copyright: © 2022. Cao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

PY - 2022

Y1 - 2022

N2 - Alzheimer’s disease (AD) is a progressive neuro-degenerative disease characterized by the impairment of cognitive function. While the pathological hallmarks of AD, amyloid plaques and neurofibrillary tangles, have been studied intensively, effective treatment for AD is still lacking. Emerging evidence suggests that gene transcriptional changes due to epigenetic abnormality during aging may play a key role in AD patho-physiology [1].

AB - Alzheimer’s disease (AD) is a progressive neuro-degenerative disease characterized by the impairment of cognitive function. While the pathological hallmarks of AD, amyloid plaques and neurofibrillary tangles, have been studied intensively, effective treatment for AD is still lacking. Emerging evidence suggests that gene transcriptional changes due to epigenetic abnormality during aging may play a key role in AD patho-physiology [1].

KW - Alzheimer’s disease

KW - Ehmt

KW - Epigenetics

KW - Histone methylation

KW - Prefrontal cortex

UR - https://www.scopus.com/pages/publications/85131443710

U2 - 10.18632/aging.204096

DO - 10.18632/aging.204096

M3 - Editorial

C2 - 35604397

AN - SCOPUS:85131443710

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VL - 14

SP - 4193

EP - 4194

JO - Aging

JF - Aging

IS - 10

ER -

Epigenetics-based treatment strategies for Alzheimer’s disease

Abstract

Keywords

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