Endocochlear Potential and Potassium Concentration Recording in Minipig Cochlea

Weiwei GUO; Chen Lei; Li Dengke; Sun Wei; Yang Shiming

doi:10.1016/S1672-2930(12)50024-3

Endocochlear Potential and Potassium Concentration Recording in Minipig Cochlea

Weiwei GUO
, Chen Lei
, Li Dengke
, Sun Wei
, Yang Shiming

Communicative Disorders and Sciences

General Hospital of People's Liberation Army
China Agricultural University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Objective: To record the endocochlear potential (EP) and calculate potassium concentration [K +] in Minipig cochleae. Methods: We used multi-barreled electrodes to measure the EP and the potential, [K +]. EP and potassium electrode recording were made in 9 cochleae from 5 minipigs to get normal EP values. Results: The average EP value in the cochlea from the minipigs was 77.3 ± 14 mV. The average [K +] for the minipigs was 147.1 ± 13 mM. Conclusions: The EP and potential, [K +] in minipigs are lower than in the human and rodents. This may be the reason why porcine ABR thresholds are slightly higher than humans and rodents.

Original language	English
Pages (from-to)	103-105
Number of pages	3
Journal	Journal of Otology
Volume	7
Issue number	2
DOIs	https://doi.org/10.1016/S1672-2930(12)50024-3
State	Published - Dec 2012

Keywords

endocochlear potential
minipig
potassium secretion
stria vascularis

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10.1016/S1672-2930(12)50024-3

Cite this

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title = "Endocochlear Potential and Potassium Concentration Recording in Minipig Cochlea",

abstract = "Objective: To record the endocochlear potential (EP) and calculate potassium concentration [K +] in Minipig cochleae. Methods: We used multi-barreled electrodes to measure the EP and the potential, [K +]. EP and potassium electrode recording were made in 9 cochleae from 5 minipigs to get normal EP values. Results: The average EP value in the cochlea from the minipigs was 77.3 ± 14 mV. The average [K +] for the minipigs was 147.1 ± 13 mM. Conclusions: The EP and potential, [K +] in minipigs are lower than in the human and rodents. This may be the reason why porcine ABR thresholds are slightly higher than humans and rodents.",

keywords = "endocochlear potential, minipig, potassium secretion, stria vascularis",

author = "Weiwei GUO and Chen Lei and Li Dengke and Sun Wei and Yang Shiming",

note = "Publisher Copyright: {\textcopyright} 2012 PLA General Hospital Department of Otolaryngology Head and Neck Surgery",

year = "2012",

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doi = "10.1016/S1672-2930(12)50024-3",

language = "English",

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T1 - Endocochlear Potential and Potassium Concentration Recording in Minipig Cochlea

AU - GUO, Weiwei

AU - Lei, Chen

AU - Dengke, Li

AU - Wei, Sun

AU - Shiming, Yang

PY - 2012/12

Y1 - 2012/12

N2 - Objective: To record the endocochlear potential (EP) and calculate potassium concentration [K +] in Minipig cochleae. Methods: We used multi-barreled electrodes to measure the EP and the potential, [K +]. EP and potassium electrode recording were made in 9 cochleae from 5 minipigs to get normal EP values. Results: The average EP value in the cochlea from the minipigs was 77.3 ± 14 mV. The average [K +] for the minipigs was 147.1 ± 13 mM. Conclusions: The EP and potential, [K +] in minipigs are lower than in the human and rodents. This may be the reason why porcine ABR thresholds are slightly higher than humans and rodents.

AB - Objective: To record the endocochlear potential (EP) and calculate potassium concentration [K +] in Minipig cochleae. Methods: We used multi-barreled electrodes to measure the EP and the potential, [K +]. EP and potassium electrode recording were made in 9 cochleae from 5 minipigs to get normal EP values. Results: The average EP value in the cochlea from the minipigs was 77.3 ± 14 mV. The average [K +] for the minipigs was 147.1 ± 13 mM. Conclusions: The EP and potential, [K +] in minipigs are lower than in the human and rodents. This may be the reason why porcine ABR thresholds are slightly higher than humans and rodents.

KW - endocochlear potential

KW - minipig

KW - potassium secretion

KW - stria vascularis

UR - https://www.scopus.com/pages/publications/85071986388

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DO - 10.1016/S1672-2930(12)50024-3

M3 - Article

AN - SCOPUS:85071986388

SN - 1672-2930

VL - 7

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EP - 105

JO - Journal of Otology

JF - Journal of Otology

IS - 2

ER -

Endocochlear Potential and Potassium Concentration Recording in Minipig Cochlea

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