Elevated serum α(1 → 3)-l-fucosyltransferase activity with synthetic low molecular weight acceptor in human ovarian cancer

Serum α(1 → 3)-l-fucosyltransferase activity was measured in 29 ovarian cancer patients with active disease, 26 ovarian cancer pateints with no clinical evidence of disease and 23 healthy females. N-Acetyl-2′-O-methyllactosamine was used as the acceptor for the enzyme. The level of the enzyme activity was significantly (P < 0.05) higher in the serum of patients with known tumor when compared to healthy controls and patients with no clinical evidence of disease.