Effects of lipopolysaccharides and prostaglandins on rat bone cell calcium and cyclic AMP

R. Dziak; E. Hausmann; Y. W. Chang

doi:10.1016/0003-9969(79)90101-8

Effects of lipopolysaccharides and prostaglandins on rat bone cell calcium and cyclic AMP

R. Dziak
, E. Hausmann
, Y. W. Chang

Department of Oral Biology

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Bone cells were isolated by collagenase digestion of 19-21 day old fetal rat calvaria. At 37 °C, lipopolysaccharides decreased Ca uptake 30-70 per cent below control values. At 4 °C, 100-900 per cent increases in Ca uptake were observed. Incubation with lipid A produced similar effects. No effects of lipopolysaccharides on cyclic AMP were noted. Prostaglandins E₁, E₂ and A₁ had no effects on calcium transport but produced characteristic increases in cyclic AMP.

Original language	English
Pages (from-to)	347-353
Number of pages	7
Journal	Archives of Oral Biology
Volume	24
Issue number	5
DOIs	https://doi.org/10.1016/0003-9969(79)90101-8
State	Published - 1979

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title = "Effects of lipopolysaccharides and prostaglandins on rat bone cell calcium and cyclic AMP",

abstract = "Bone cells were isolated by collagenase digestion of 19-21 day old fetal rat calvaria. At 37 °C, lipopolysaccharides decreased Ca uptake 30-70 per cent below control values. At 4 °C, 100-900 per cent increases in Ca uptake were observed. Incubation with lipid A produced similar effects. No effects of lipopolysaccharides on cyclic AMP were noted. Prostaglandins E1, E2 and A1 had no effects on calcium transport but produced characteristic increases in cyclic AMP.",

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AU - Dziak, R.

AU - Hausmann, E.

AU - Chang, Y. W.

PY - 1979

Y1 - 1979

N2 - Bone cells were isolated by collagenase digestion of 19-21 day old fetal rat calvaria. At 37 °C, lipopolysaccharides decreased Ca uptake 30-70 per cent below control values. At 4 °C, 100-900 per cent increases in Ca uptake were observed. Incubation with lipid A produced similar effects. No effects of lipopolysaccharides on cyclic AMP were noted. Prostaglandins E1, E2 and A1 had no effects on calcium transport but produced characteristic increases in cyclic AMP.

AB - Bone cells were isolated by collagenase digestion of 19-21 day old fetal rat calvaria. At 37 °C, lipopolysaccharides decreased Ca uptake 30-70 per cent below control values. At 4 °C, 100-900 per cent increases in Ca uptake were observed. Incubation with lipid A produced similar effects. No effects of lipopolysaccharides on cyclic AMP were noted. Prostaglandins E1, E2 and A1 had no effects on calcium transport but produced characteristic increases in cyclic AMP.

UR - https://www.scopus.com/pages/publications/0018697444

U2 - 10.1016/0003-9969(79)90101-8

DO - 10.1016/0003-9969(79)90101-8

M3 - Article

C2 - 229812

AN - SCOPUS:0018697444

SN - 0003-9969

VL - 24

SP - 347

EP - 353

JO - Archives of Oral Biology

JF - Archives of Oral Biology

IS - 5

ER -

Effects of lipopolysaccharides and prostaglandins on rat bone cell calcium and cyclic AMP

Abstract

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