Effects of cocaethylene on dopamine and serotonin synthesis in Long- Evans and Sprague-Dawley brains

Michael H. Baumann; Judith M. Horowitz; Mark B. Kristal; German Torres

doi:10.1016/S0006-8993(98)00714-8

Effects of cocaethylene on dopamine and serotonin synthesis in Long- Evans and Sprague-Dawley brains

Michael H. Baumann
, Judith M. Horowitz
, Mark B. Kristal
, German Torres

Psychology

Clinical Psychopharmacology Section
SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

We examined the behavioral and neurochemical effects of cocaethylene treatment in Long-Evans (LE) and Sprague-Dawley (SD) rats. Cocaethylene- induced behaviours were significantly less in LE rats. Cocaethylene caused an inhibition of dopamine synthesis in the caudate nucleus and nucleus accumbens that was equivalent in both rat lines. Serotinin synthesis was also suppressed by cocaethylene treatment, however this phenomenon was less pronounced when compared with the effects on dopamine synthesis.

Original language	English
Pages (from-to)	316-319
Number of pages	4
Journal	Brain Research
Volume	804
Issue number	2
DOIs	https://doi.org/10.1016/S0006-8993(98)00714-8
State	Published - Sep 7 1998

Keywords

Behavior
Caudate nucleus
Cingulate cortex
Genotype
Nucleus accumbens

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10.1016/S0006-8993(98)00714-8

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title = "Effects of cocaethylene on dopamine and serotonin synthesis in Long- Evans and Sprague-Dawley brains",

abstract = "We examined the behavioral and neurochemical effects of cocaethylene treatment in Long-Evans (LE) and Sprague-Dawley (SD) rats. Cocaethylene- induced behaviours were significantly less in LE rats. Cocaethylene caused an inhibition of dopamine synthesis in the caudate nucleus and nucleus accumbens that was equivalent in both rat lines. Serotinin synthesis was also suppressed by cocaethylene treatment, however this phenomenon was less pronounced when compared with the effects on dopamine synthesis.",

keywords = "Behavior, Caudate nucleus, Cingulate cortex, Genotype, Nucleus accumbens",

author = "Baumann, \{Michael H.\} and Horowitz, \{Judith M.\} and Kristal, \{Mark B.\} and German Torres",

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T1 - Effects of cocaethylene on dopamine and serotonin synthesis in Long- Evans and Sprague-Dawley brains

AU - Baumann, Michael H.

AU - Horowitz, Judith M.

AU - Kristal, Mark B.

AU - Torres, German

PY - 1998/9/7

Y1 - 1998/9/7

N2 - We examined the behavioral and neurochemical effects of cocaethylene treatment in Long-Evans (LE) and Sprague-Dawley (SD) rats. Cocaethylene- induced behaviours were significantly less in LE rats. Cocaethylene caused an inhibition of dopamine synthesis in the caudate nucleus and nucleus accumbens that was equivalent in both rat lines. Serotinin synthesis was also suppressed by cocaethylene treatment, however this phenomenon was less pronounced when compared with the effects on dopamine synthesis.

AB - We examined the behavioral and neurochemical effects of cocaethylene treatment in Long-Evans (LE) and Sprague-Dawley (SD) rats. Cocaethylene- induced behaviours were significantly less in LE rats. Cocaethylene caused an inhibition of dopamine synthesis in the caudate nucleus and nucleus accumbens that was equivalent in both rat lines. Serotinin synthesis was also suppressed by cocaethylene treatment, however this phenomenon was less pronounced when compared with the effects on dopamine synthesis.

KW - Behavior

KW - Caudate nucleus

KW - Cingulate cortex

KW - Genotype

KW - Nucleus accumbens

UR - https://www.scopus.com/pages/publications/0032494267

U2 - 10.1016/S0006-8993(98)00714-8

DO - 10.1016/S0006-8993(98)00714-8

M3 - Article

C2 - 9757074

AN - SCOPUS:0032494267

SN - 0006-8993

VL - 804

SP - 316

EP - 319

JO - Brain Research

JF - Brain Research

IS - 2

ER -

Effects of cocaethylene on dopamine and serotonin synthesis in Long- Evans and Sprague-Dawley brains

Abstract

Keywords

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