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Effects of chronic ethanol consumption on the rat parotid gland

  • J. A. Banderas
  • , L. A. Gaitan
  • , J. Portilla
  • , A. Aguirre
  • Universidad Nacional Autónoma de México
  • SUNY Buffalo

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Two-month-old Wistar rats ingested 10% ethanol for 12 months. Their parotid glands were then compared with those of normal controls by light microscopy. They had extensive ductal and acinar oncocytic transformation; numerous atypical acinar cells showed anisocytosis, polyploidism and hyperchromatism, features that were absent in controls. Oncocytosis and atypical acinar cells have been reported in 2-3-yr-old ('senile') Wistar rats. Thus, chronic alcohol ingestion may produce cellular features resembling those observed in the parotid gland of 'senile' Wistar rats.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalArchives of Oral Biology
Volume37
Issue number1
DOIs
StatePublished - Jan 1992

Keywords

  • ageing
  • alcohol
  • alcoholism
  • cellular pleomorphism
  • chronic
  • histology
  • morphology
  • oncocytosis
  • parotid glands
  • rat
  • senescence

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