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Effect of dietary sodium reduction on red blood cell sodium concentration and sodium-lithium countertransport

  • Richard Cooper
  • , Maurizio Trevisan
  • , Linda Van Horn
  • , Emmanuel Larbi
  • , Kiang Liu
  • , Seraphim Nanas
  • , Hirotsugu Ueshima
  • , Christopher Sempos
  • , David Ostrow
  • , Jeremiah Stamler
  • Northwestern University
  • VA Medical Center

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

A randomized, crossover trial was carried out on the effect of moderate sodium reduction on red-blood-cell sodium metabolism. The participants were healthy high school students (mean age = 16 years, n = 33). Changes in sodium-lithium countertransport and intracellular sodium concentration were evaluated 24 days after a decrease in dietary sodium from approximately 110 to 40 mEq per day. Dietary sodium restriction had no significant effect on either sodium-lithium countertransport or intracellular sodium concentration.

Original languageEnglish
Pages (from-to)731-735
Number of pages5
JournalHypertension
Volume6
Issue number5
DOIs
StatePublished - 1984

Keywords

  • Blood pressure
  • Countertransport
  • Randomized trial
  • Sodium

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