Distribution, regulation and role of the agmatine deiminase system in mutans streptococci

A. R. Griswold; M. M. Nascimento; R. A. Burne

doi:10.1111/j.1399-302X.2008.00459.x

Distribution, regulation and role of the agmatine deiminase system in mutans streptococci

A. R. Griswold
, M. M. Nascimento
, R. A. Burne

Restorative Dentistry Administration

University of Florida

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The agmatine deiminase system (AgDS) was identified in seven strains of mutans streptococci. Genes encoding the AgDS of Streptococcus rattus FA-1 were sequenced and found to share homology with the agu genes of Streptococcus mutans UA159. With the exception of Streptococcus sobrinus, the AgDS of mutans streptococci appear to be sensitive to carbohydrate catabolite repression. Agmatine inhibited bacterial growth, suggesting that the AgDS degrades a deleterious substance into useful compounds.

Original language	English
Pages (from-to)	79-82
Number of pages	4
Journal	Oral Microbiology and Immunology
Volume	24
Issue number	1
DOIs	https://doi.org/10.1111/j.1399-302X.2008.00459.x
State	Published - Feb 2009

Keywords

Biofilm
Dental caries
Ecology

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10.1111/j.1399-302X.2008.00459.x

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abstract = "The agmatine deiminase system (AgDS) was identified in seven strains of mutans streptococci. Genes encoding the AgDS of Streptococcus rattus FA-1 were sequenced and found to share homology with the agu genes of Streptococcus mutans UA159. With the exception of Streptococcus sobrinus, the AgDS of mutans streptococci appear to be sensitive to carbohydrate catabolite repression. Agmatine inhibited bacterial growth, suggesting that the AgDS degrades a deleterious substance into useful compounds.",

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AB - The agmatine deiminase system (AgDS) was identified in seven strains of mutans streptococci. Genes encoding the AgDS of Streptococcus rattus FA-1 were sequenced and found to share homology with the agu genes of Streptococcus mutans UA159. With the exception of Streptococcus sobrinus, the AgDS of mutans streptococci appear to be sensitive to carbohydrate catabolite repression. Agmatine inhibited bacterial growth, suggesting that the AgDS degrades a deleterious substance into useful compounds.

KW - Biofilm

KW - Dental caries

KW - Ecology

UR - https://www.scopus.com/pages/publications/57649178198

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ER -

Distribution, regulation and role of the agmatine deiminase system in mutans streptococci

Abstract

Keywords

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