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Diffuse histiocytic lymphoma in a patient treated with cyclophosphamide for Wegener's granulomatosis

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Abstract

Diffuse histiocytic lymphoma developed in a 48-year-old man with Wegener's granulomatosis after nine years of therapy with cyclophosphamide. He died despite aggressive surgical and medical therapy for the lymphoma. This may be the first report of diffuse histiocytic lymphoma following treatment of Wegener's granulomatosis with Cyclophosphamide. Recommendations for the approach towards extended therapy of smoldering Wegener's granulomatosis are discussed.

Original languageEnglish
Pages (from-to)745-747
Number of pages3
JournalAmerican Journal of Medicine
Volume76
Issue number4
DOIs
StatePublished - Apr 1984

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