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Development of FuGO: An ontology for functional genomics investigations

  • Patricia L. Whetzel
  • , Ryan A. Brinkman
  • , Helen C. Causton
  • , Liju Fan
  • , Dawn Field
  • , Jennifer Fostel
  • , Gilberto Fragoso
  • , Tanya Gray
  • , Mervi Heiskanen
  • , Tina Hernandez-Boussard
  • , Norman Morrison
  • , Helen Parkinson
  • , Philippe Rocca-Serra
  • , Susanna Assunta Sansone
  • , Daniel Schober
  • , Barry Smith
  • , Robert Stevens
  • , Christian J. Stoeckert
  • , Chris Taylor
  • , Joe White
  • Andrew Wood
  • University of Pennsylvania
  • Terry Fox Laboratory
  • Imperial College London
  • Ontology Workshop, LLC
  • Centre for Ecology and Hydrology
  • National Institutes of Health
  • Stanford University
  • University of Manchester
  • European Molecular Biology Laboratory
  • Dana-Farber Cancer Institute

Research output: Contribution to journalReview articlepeer-review

53 Scopus citations

Abstract

The development of the Functional Genomics Investigation Ontology (FuGO) is a collaborative, international effort that will provide a resource for annotating functional genomics investigations, including the study design, protocols and instrumentation used, the data generated and the types of analysis performed on the data. FuGO will contain both terms that are universal to all functional genomics investigations and those that are domain specific. In this way, the ontology will serve as the "semantic glue" to provide a common understanding of data from across these disparate data sources. In addition, FuGO will reference out to existing mature ontologies to avoid the need to duplicate these resources, and will do so in such a way as to enable their ease of use in annotation. This project is in the early stages of development; the paper will describe efforts to initiate the project; One scope and organization of the projects the work accomplished to date, and the challenges encountered, as well as future plans.

Original languageEnglish
Pages (from-to)199-204
Number of pages6
JournalOMICS A Journal of Integrative Biology
Volume10
Issue number2
DOIs
StatePublished - 2006

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