TY - GEN
T1 - Development of an atmospheric pressure non-thermal plasma needle for melanoma cell research
AU - Zirnheld, Jennifer L.
AU - DiSanto, Thomas M.
AU - Burke, Kevin M.
AU - Zucker, Shoshanna N.
AU - Etemadi, Kasra
PY - 2009
Y1 - 2009
N2 - An atmospheric pressure non-thermal plasma needle has been developed to study the potential impact of plasma on melanoma cancer cells. The device operates at a frequency of 113 kHz with the plasma sustaining electrode at a potential of approximately 2.5 kV ac and a power less than 1.5W. The plasma is generated by ionizing helium gas with flow rates in the range of 1-9.7 L/min. The plasma needle was applied to cultured metastatic 1205Lu melanoma cells as well as Human Primary Keratinocytes (HEK) within an inverted microscope chamber. Time lapse photography was utilized to record cell death. Preliminary results show approximately a 5-fold killing effect of the melanoma cells as compared to keratinocytes.
AB - An atmospheric pressure non-thermal plasma needle has been developed to study the potential impact of plasma on melanoma cancer cells. The device operates at a frequency of 113 kHz with the plasma sustaining electrode at a potential of approximately 2.5 kV ac and a power less than 1.5W. The plasma is generated by ionizing helium gas with flow rates in the range of 1-9.7 L/min. The plasma needle was applied to cultured metastatic 1205Lu melanoma cells as well as Human Primary Keratinocytes (HEK) within an inverted microscope chamber. Time lapse photography was utilized to record cell death. Preliminary results show approximately a 5-fold killing effect of the melanoma cells as compared to keratinocytes.
UR - https://www.scopus.com/pages/publications/77950018947
U2 - 10.1109/PPC.2009.5386395
DO - 10.1109/PPC.2009.5386395
M3 - Conference contribution
AN - SCOPUS:77950018947
SN - 9781424440658
T3 - PPC2009 - 17th IEEE International Pulsed Power Conference
SP - 1429
EP - 1432
BT - PPC2009 - 17th IEEE International Pulsed Power Conference
T2 - 17th IEEE International Pulsed Power Conference, PPC2009
Y2 - 28 June 2009 through 2 July 2009
ER -