Abstract
A microcantilever modified with a layer of acetyl cholinesterase (AChE) responding to paraoxon is reported in this work. Acetyl cholinesterase was immobilized on a microcantilever through a cross linker to a monolayer on gold surface of the microcantilever. The microcantilever underwent a maximum of 7 nm bending due to the inhibition of AChE by paraoxon that slightly changed the conformation of AChE.
| Original language | English |
|---|---|
| Pages (from-to) | 175-183 |
| Number of pages | 9 |
| Journal | Instrumentation Science and Technology |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 2004 |
Keywords
- Acetyl cholinesterase (AChE)
- Adsorption-induced stress
- Microcantilever
- Organophosphate detection
- Self-assembled monolayers (SAMs)
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