Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells

Peng An; Zhipeng Yu; Qing Lin

doi:10.1039/c3cc45752d

Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells

Peng An
, Zhipeng Yu
, Qing Lin

Chemistry

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Abstract

A 405 nm light-activatable terthiophene-based tetrazole was designed that reacts with a fumarate dipolarophile with the second-order rate constant k₂ exceeding 10³ M⁻¹ s⁻¹. The utility of this laser-activatable tetrazole in imaging microtubules in a spatiotemporally controlled manner in live cells was demonstrated.

Original language	English
Pages (from-to)	9920-9922
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	85
DOIs	https://doi.org/10.1039/c3cc45752d
State	Published - Oct 2013

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10.1039/c3cc45752d

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title = "Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells",

abstract = "A 405 nm light-activatable terthiophene-based tetrazole was designed that reacts with a fumarate dipolarophile with the second-order rate constant k2 exceeding 103 M−1 s−1. The utility of this laser-activatable tetrazole in imaging microtubules in a spatiotemporally controlled manner in live cells was demonstrated.",

author = "Peng An and Zhipeng Yu and Qing Lin",

year = "2013",

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AU - An, Peng

AU - Yu, Zhipeng

AU - Lin, Qing

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AB - A 405 nm light-activatable terthiophene-based tetrazole was designed that reacts with a fumarate dipolarophile with the second-order rate constant k2 exceeding 103 M−1 s−1. The utility of this laser-activatable tetrazole in imaging microtubules in a spatiotemporally controlled manner in live cells was demonstrated.

UR - https://www.scopus.com/pages/publications/84885165332

U2 - 10.1039/c3cc45752d

DO - 10.1039/c3cc45752d

M3 - Article

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AN - SCOPUS:84885165332

SN - 1359-7345

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SP - 9920

EP - 9922

JO - Chemical Communications

JF - Chemical Communications

IS - 85

ER -

Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells

Abstract

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