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Deep-tissue photoacoustic imaging at 1064 nm using a contrast agent based on phosphorus phthalocyanine formulation

  • SUNY Buffalo
  • Ministry of Education of the People's Republic of China

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

This study demonstrated the performance of photoacoustic imaging at 1064 nm using phosphorus phthalocyanine (P-Pc), a contrast agent with strong absorption at 1064 nm. Due to high maximum permissible exposure of 1064 nm laser light and strong absorbance of P-Pc at 1064 nm, we demonstrated an imaging depth of 11.6 cm in chicken breast tissue. For animal imaging, we used P-Pc to target tumor and to track intestine dynamics. Thus, using a contrast medium with extreme absorption at 1064 nm readily enables high quality photoacoustic imaging at exceptional depths.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2017
EditorsAlexander A. Oraevsky, Lihong V. Wang
PublisherSPIE
ISBN (Electronic)9781510605695
DOIs
StatePublished - 2017
EventPhotons Plus Ultrasound: Imaging and Sensing 2017 - San Francisco, United States
Duration: Jan 29 2017Feb 1 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10064
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2017
Country/TerritoryUnited States
CitySan Francisco
Period01/29/1702/1/17

Keywords

  • 1064 nm
  • Deep tissue
  • Photoacoustic imaging

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