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Decoys 'R' Us: A database of incorrect conformations to improve protein structure prediction

  • Stanford University

Research output: Contribution to journalArticlepeer-review

197 Scopus citations

Abstract

The development of an energy or scoring function for protein structure prediction is greatly enhanced by testing the function on a set of computer- generated conformations (decoys) to determine whether it can readily distinguish native-like conformations from nonnative ones. We have created 'Decoys 'R' Us,' a database containing many such sets of conformations, to provide a resource that allows scoring functions to be improved.

Original languageEnglish
Pages (from-to)1399-1401
Number of pages3
JournalProtein Science
Volume9
Issue number7
DOIs
StatePublished - 2000

Keywords

  • Refinement
  • Scoring/energy functions

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