Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420)

Sophie Belin; Francesca Ornaghi; Ghjuvan'Ghjacumu Shackleford; Jie Wang; Cristina Scapin; Camila Lopez-Anido; Nicholas Silvestri; Neil Robertson; Courtney Williamson; Akihiro Ishii; Carla Taveggia; John Svaren; Rashmi Bansal; Markus H. Schwab; Klaus Nave; Pietro Fratta; Maurizio D'Antonio; Yannick Poitelon; M. Laura Feltri; Lawrence Wrabetz

doi:10.1093/hmg/ddz037

Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420)

Sophie Belin
, Francesca Ornaghi
, Ghjuvan'Ghjacumu Shackleford
, Jie Wang
, Cristina Scapin
, Camila Lopez-Anido
, Nicholas Silvestri
, Neil Robertson
, Courtney Williamson
, Akihiro Ishii
, Carla Taveggia
, John Svaren
, Rashmi Bansal
, Markus H. Schwab
, Klaus Nave
, Pietro Fratta
, Maurizio D'Antonio
, Yannick Poitelon
, M. Laura Feltri
, Lawrence Wrabetz

Neurology

SUNY Buffalo
Albany Medical College
San Raffaele Scientific Institute
University of Wisconsin-Madison
University of Connecticut
Max Planck Institute of Experimental Medicine
Hannover Medical School
University College London

Research output: Contribution to journal › Comment/debate

Abstract

The authors wish to apologize for errors in the legend of Figure 7. The legend has been corrected to the following: Figure 7. Expression of HA-NRG1 type III transgene increases PMP2 protein level (A) Western blot analysis from WT, Nrg1t3, Q215X, Nrg1t3;Q215X, Mek1DD;P0Cre and Mek1DD;P0Cre;Q215X sciatic nerves at one month. Expression of HA-NRG1t3 transgene in sciatic nerves or constitutive activation the MAPK/ERK pathway in Schwann cells leads to an increase in ERK phosphorylation, a decrease in EGR2 protein levels and an increase in PMP2 protein levels. These effects are enhanced in Mek1DD;P0Cremutants as compared to HANRG1t3 mutants.Western blots were cropped. Semithin cross-sections stained with toluidine blue (B) and nerve conduction velocity (C) from wildtype (WT), Nrg1t3 hemizygote (Nrg1t3), P0Q215X heterozygote (Q215X) and Nrg1t3 hemizygote and P0Q215X heterozygote (Nrg1t3;Q215X) sciatic nerves at one year.

Original language	English
Pages (from-to)	2282
Number of pages	1
Journal	Human Molecular Genetics
Volume	28
Issue number	13
DOIs	https://doi.org/10.1093/hmg/ddz037
State	Published - Jul 1 2019

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Belin, S., Ornaghi, F., Shackleford, GG., Wang, J., Scapin, C., Lopez-Anido, C., Silvestri, N., Robertson, N., Williamson, C., Ishii, A., Taveggia, C., Svaren, J., Bansal, R., Schwab, M. H., Nave, K., Fratta, P., D'Antonio, M., Poitelon, Y., Feltri, M. L., & Wrabetz, L. (2019). Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420). Human Molecular Genetics, 28(13), 2282. https://doi.org/10.1093/hmg/ddz037

@article{364ff35c4d56465892fb162e9d2f42c0,

title = "Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420)",

abstract = "The authors wish to apologize for errors in the legend of Figure 7. The legend has been corrected to the following: Figure 7. Expression of HA-NRG1 type III transgene increases PMP2 protein level (A) Western blot analysis from WT, Nrg1t3, Q215X, Nrg1t3;Q215X, Mek1DD;P0Cre and Mek1DD;P0Cre;Q215X sciatic nerves at one month. Expression of HA-NRG1t3 transgene in sciatic nerves or constitutive activation the MAPK/ERK pathway in Schwann cells leads to an increase in ERK phosphorylation, a decrease in EGR2 protein levels and an increase in PMP2 protein levels. These effects are enhanced in Mek1DD;P0Cremutants as compared to HANRG1t3 mutants.Western blots were cropped. Semithin cross-sections stained with toluidine blue (B) and nerve conduction velocity (C) from wildtype (WT), Nrg1t3 hemizygote (Nrg1t3), P0Q215X heterozygote (Q215X) and Nrg1t3 hemizygote and P0Q215X heterozygote (Nrg1t3;Q215X) sciatic nerves at one year.",

author = "Sophie Belin and Francesca Ornaghi and Ghjuvan'Ghjacumu Shackleford and Jie Wang and Cristina Scapin and Camila Lopez-Anido and Nicholas Silvestri and Neil Robertson and Courtney Williamson and Akihiro Ishii and Carla Taveggia and John Svaren and Rashmi Bansal and Schwab, \{Markus H.\} and Klaus Nave and Pietro Fratta and Maurizio D'Antonio and Yannick Poitelon and Feltri, \{M. Laura\} and Lawrence Wrabetz",

year = "2019",

month = jul,

day = "1",

doi = "10.1093/hmg/ddz037",

language = "English",

volume = "28",

pages = "2282",

journal = "Human Molecular Genetics",

issn = "0964-6906",

publisher = "Oxford University Press",

number = "13",

}

Belin, S, Ornaghi, F, Shackleford, GG, Wang, J, Scapin, C, Lopez-Anido, C, Silvestri, N, Robertson, N, Williamson, C, Ishii, A, Taveggia, C, Svaren, J, Bansal, R, Schwab, MH, Nave, K, Fratta, P, D'Antonio, M, Poitelon, Y, Feltri, ML & Wrabetz, L 2019, 'Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420)', Human Molecular Genetics, vol. 28, no. 13, pp. 2282. https://doi.org/10.1093/hmg/ddz037

Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420). / Belin, Sophie; Ornaghi, Francesca; Shackleford, Ghjuvan'Ghjacumu et al.
In: Human Molecular Genetics, Vol. 28, No. 13, 01.07.2019, p. 2282.

Research output: Contribution to journal › Comment/debate

TY - JOUR

T1 - Corrigendum

T2 - Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420)

AU - Belin, Sophie

AU - Ornaghi, Francesca

AU - Shackleford, Ghjuvan'Ghjacumu

AU - Wang, Jie

AU - Scapin, Cristina

AU - Lopez-Anido, Camila

AU - Silvestri, Nicholas

AU - Robertson, Neil

AU - Williamson, Courtney

AU - Ishii, Akihiro

AU - Taveggia, Carla

AU - Svaren, John

AU - Bansal, Rashmi

AU - Schwab, Markus H.

AU - Nave, Klaus

AU - Fratta, Pietro

AU - D'Antonio, Maurizio

AU - Poitelon, Yannick

AU - Feltri, M. Laura

AU - Wrabetz, Lawrence

PY - 2019/7/1

Y1 - 2019/7/1

N2 - The authors wish to apologize for errors in the legend of Figure 7. The legend has been corrected to the following: Figure 7. Expression of HA-NRG1 type III transgene increases PMP2 protein level (A) Western blot analysis from WT, Nrg1t3, Q215X, Nrg1t3;Q215X, Mek1DD;P0Cre and Mek1DD;P0Cre;Q215X sciatic nerves at one month. Expression of HA-NRG1t3 transgene in sciatic nerves or constitutive activation the MAPK/ERK pathway in Schwann cells leads to an increase in ERK phosphorylation, a decrease in EGR2 protein levels and an increase in PMP2 protein levels. These effects are enhanced in Mek1DD;P0Cremutants as compared to HANRG1t3 mutants.Western blots were cropped. Semithin cross-sections stained with toluidine blue (B) and nerve conduction velocity (C) from wildtype (WT), Nrg1t3 hemizygote (Nrg1t3), P0Q215X heterozygote (Q215X) and Nrg1t3 hemizygote and P0Q215X heterozygote (Nrg1t3;Q215X) sciatic nerves at one year.

AB - The authors wish to apologize for errors in the legend of Figure 7. The legend has been corrected to the following: Figure 7. Expression of HA-NRG1 type III transgene increases PMP2 protein level (A) Western blot analysis from WT, Nrg1t3, Q215X, Nrg1t3;Q215X, Mek1DD;P0Cre and Mek1DD;P0Cre;Q215X sciatic nerves at one month. Expression of HA-NRG1t3 transgene in sciatic nerves or constitutive activation the MAPK/ERK pathway in Schwann cells leads to an increase in ERK phosphorylation, a decrease in EGR2 protein levels and an increase in PMP2 protein levels. These effects are enhanced in Mek1DD;P0Cremutants as compared to HANRG1t3 mutants.Western blots were cropped. Semithin cross-sections stained with toluidine blue (B) and nerve conduction velocity (C) from wildtype (WT), Nrg1t3 hemizygote (Nrg1t3), P0Q215X heterozygote (Q215X) and Nrg1t3 hemizygote and P0Q215X heterozygote (Nrg1t3;Q215X) sciatic nerves at one year.

UR - https://www.scopus.com/pages/publications/85068490569

U2 - 10.1093/hmg/ddz037

DO - 10.1093/hmg/ddz037

M3 - Comment/debate

C2 - 31220267

AN - SCOPUS:85068490569

SN - 0964-6906

VL - 28

SP - 2282

JO - Human Molecular Genetics

JF - Human Molecular Genetics

IS - 13

ER -

Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy (Human Molecular Genetics (2019) 28:8 (1260-1273) DOI: 10.1093/hmg/ddy420)

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