Abstract
In the original publication [1], there was a mistake in Figure 3A as published. The two colony images in the lower panel were similar. The corrected Figure 3A appears below. The corresponding Figure 3 legend has been updated to reflect the removal of some of the clonogenic assays. Figure 3. R2 sensitized HCT116 cells to M13 and Nutlin. A clonogenicity assay was performed on HCT116p53+/+ cells or HCT116p53−/− treated for one week either with R2 alone, M13 alone, or with a combination of R2 and M13 (A), and R2 alone, Nutlin-1 alone, or with a combination of R2 and Nutlin-1 (B). The representative clonogenicity assay of several independent experiments is shown. A clonogenicity assay image of HCT116p53−/− in (A) is not shown. Colonies were counted and quantification is shown with the panels on the right. Bars show the average number of colonies per treatment from two to four independent experiments. * Student’s t-test, p < 0.05, R2 + M13 or R2 + Nutlin-1 versus untreated HCT116p53+/+ and HCT116 p53−/− or treated cells with a single agent. The p-values are shown in a combination group versus a single agent. The text in Section 2.2 The R2 Sensitized Cancer Cells to M13 (Disrupting FAK and Mdm-2) and Nutlin-1 (Disrupting p53 and Mdm-2) Treatments, paragraph 2 has been updated to ‘Since Nutlin-1 that disrupts p53 and Mdm-2 protein interaction [15], also can induce p53, we treated HCT116 p53+/+ and HCT53−/− cells with either R2 alone, Nutlin-1 alone or with combination of R2 and Nutlin-1 (Figure 3B)’. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
| Original language | English |
|---|---|
| Article number | 526 |
| Journal | Cancers |
| Volume | 18 |
| Issue number | 3 |
| DOIs |
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| State | Published - Feb 2026 |
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