Converting p53 from a killer into a healer

Andrei V. Gudkov

doi:10.1038/nm1102-1196

Converting p53 from a killer into a healer

Andrei V. Gudkov

Roswell Park - Cell Stress and Biophysical Oncology

Research output: Contribution to journal › Short survey › peer-review

43 Scopus citations

Abstract

Selenium-containing compounds are in phase 2 and 3 clinical trials for prostate cancer prevention, although it is unclear how they work. A study suggests that selenium can facilitate DNA repair by activating the p53 tumor suppressor in an unusual way.

Original language	English
Pages (from-to)	1196-1198
Number of pages	3
Journal	Nature Medicine
Volume	8
Issue number	11
DOIs	https://doi.org/10.1038/nm1102-1196
State	Published - Nov 1 2002

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title = "Converting p53 from a killer into a healer",

abstract = "Selenium-containing compounds are in phase 2 and 3 clinical trials for prostate cancer prevention, although it is unclear how they work. A study suggests that selenium can facilitate DNA repair by activating the p53 tumor suppressor in an unusual way.",

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Converting p53 from a killer into a healer

Abstract

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