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Continuous-flow in-droplet magnetic particle separation in a droplet-based microfluidic platform

  • SUNY Buffalo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

We demonstrate a droplet-based microfluidic device in which in-droplet magnetic bead separation is performed in continuous-flow. Two droplets containing different solution for the magnetic bead separation are generated in pair-wise manner. Sequential fusion of droplets occurs by a geometrical structure. The magnetic beads are deflected by externally applied magnetic force from one side of droplet to the other. The droplets are split into two daughter droplets, separating magnetic beads at a T-junction. In the experiments we analyze working zone for the separation, adjusting magnet position and total flow rate and measure separation error rate for the optimization of the device.

Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages948-950
Number of pages3
StatePublished - 2011
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: Oct 2 2011Oct 6 2011

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume2

Conference

Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Country/TerritoryUnited States
CitySeattle, WA
Period10/2/1110/6/11

Keywords

  • Continuous Flow
  • Droplet
  • Magnetic Bead
  • Separation
  • Splitting

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