TY - GEN
T1 - Comparison of intensity based similarity measures for matching genomic structures in microscopic images of living cells
AU - Bhattacharya, Sambit
AU - Acharya, Raj
AU - Pliss, Artem
AU - Malyavantham, Kishore S.
AU - Berezney, Ronald
PY - 2006
Y1 - 2006
N2 - This paper presents our comparative study of the application of intensity based similarity measures to the problem of matching genomic structures in microscopic images of living cells. As part of our ongoing research [7], [8] we present here for the first time evidence from experiments and simulations that show the benefit of using an iterative matching algorithm guided by an intensity based similarity measure. Our experimental results are compared against a gold standard and suggest the measures that work best in the presence of fluorescent decay and other problems inherent to time-lapse microscopy. This makes our approach widely applicable in the study of the dynamics of living cells with time-lapse microscopic imaging.
AB - This paper presents our comparative study of the application of intensity based similarity measures to the problem of matching genomic structures in microscopic images of living cells. As part of our ongoing research [7], [8] we present here for the first time evidence from experiments and simulations that show the benefit of using an iterative matching algorithm guided by an intensity based similarity measure. Our experimental results are compared against a gold standard and suggest the measures that work best in the presence of fluorescent decay and other problems inherent to time-lapse microscopy. This makes our approach widely applicable in the study of the dynamics of living cells with time-lapse microscopic imaging.
UR - https://www.scopus.com/pages/publications/34047154663
U2 - 10.1109/IEMBS.2006.260165
DO - 10.1109/IEMBS.2006.260165
M3 - Conference contribution
C2 - 17946542
AN - SCOPUS:34047154663
SN - 1424400325
SN - 9781424400324
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 3057
EP - 3061
BT - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
T2 - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Y2 - 30 August 2006 through 3 September 2006
ER -