TY - GEN
T1 - CMOS direct time interval measurement of long-lived luminescence lifetimes
AU - Yao, Lei
AU - Yung, Ka Yi
AU - Cheung, Maurice C.
AU - Chodavarapu, Vamsy P.
AU - Bright, Frank V.
PY - 2011
Y1 - 2011
N2 - We describe a Complementary Metal-Oxide Semiconductor (CMOS) Direct Time Interval Measurement (DTIM) Integrated Circuit (IC) to detect the decay (fall) time of the luminescence emission when analyte-sensitive luminophores are excited with an optical pulse. The CMOS DTIM IC includes 1414 phototransistor array, transimpedance amplifier, regulated gain amplifier, fall time detector, and time-to-digital convertor. We examined the DTIM system to measure the emission lifetime of oxygen-sensitive luminophores tris(4,7-diphenyl-1, 10-phenanthroline) ruthenium(II) ([Ru(dpp)3]2) encapsulated in sol-gel derived xerogel thin-films. The DTIM system fabricated using TSMC 0.35m process functions to detect lifetimes from 4s to 14.4s but can be tuned to detect longer lifetimes. The system provides 8-bit digital output proportional to lifetimes and consumes 4.5mW of power with 3.3V DC supply. The CMOS system provides a useful platform for the development of reliable, robust, and miniaturized optical chemical sensors.
AB - We describe a Complementary Metal-Oxide Semiconductor (CMOS) Direct Time Interval Measurement (DTIM) Integrated Circuit (IC) to detect the decay (fall) time of the luminescence emission when analyte-sensitive luminophores are excited with an optical pulse. The CMOS DTIM IC includes 1414 phototransistor array, transimpedance amplifier, regulated gain amplifier, fall time detector, and time-to-digital convertor. We examined the DTIM system to measure the emission lifetime of oxygen-sensitive luminophores tris(4,7-diphenyl-1, 10-phenanthroline) ruthenium(II) ([Ru(dpp)3]2) encapsulated in sol-gel derived xerogel thin-films. The DTIM system fabricated using TSMC 0.35m process functions to detect lifetimes from 4s to 14.4s but can be tuned to detect longer lifetimes. The system provides 8-bit digital output proportional to lifetimes and consumes 4.5mW of power with 3.3V DC supply. The CMOS system provides a useful platform for the development of reliable, robust, and miniaturized optical chemical sensors.
UR - https://www.scopus.com/pages/publications/84861947499
U2 - 10.1109/IEMBS.2011.6089883
DO - 10.1109/IEMBS.2011.6089883
M3 - Conference contribution
C2 - 22254237
AN - SCOPUS:84861947499
SN - 9781424441211
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 5
EP - 9
BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Y2 - 30 August 2011 through 3 September 2011
ER -