@inproceedings{8eaf402f47a04a52a2b8b35d4de32cec,
title = "CMOS-based biosensor systems using integrated nanostructured recognition elements",
abstract = "Rapid advances in point-of-care devices for medical and biomedical diagnostic and therapeutic applications have increased the need for low cost, low power, high throughput, and miniaturized systems. To this end, we developed several optical sensor systems using CMOS detection and processing components and sol-gel derived xerogel recognition elements for monitoring various biochemical analytes. These sensors are based either on the measurement of the luminescence intensity or the excited-state lifetimes of luminophores embedded in the nanostructured xerogel matrices. Specifically, the design and development of CMOS detection and signal processing components and their system integration will be described in detail. Additionally, we will describe the factors that limit the performance of these sensor systems in terms of sensitivity, response time, and dynamic range. Finally, the results obtained for monitoring important biochemical analytes such as oxygen (O2) and glucose will be discussed.",
keywords = "Biochemical sensors, CMOS sensors, Glucose sensor, Nanostructured sensors, Optical sensors, Oxygen sensor, Phase Fluorometry, Xerogel",
author = "Chodavarapu, \{Vamsy P.\} and Shubin, \{Daniil O.\} and Bukowski, \{Rachel M.\} and Tehan, \{Elizabeth C.\} and Titus, \{Albert H.\} and Cartwright, \{Alexander N.\} and Bright, \{Frank V.\}",
year = "2006",
doi = "10.1117/12.649907",
language = "English",
isbn = "0819461377",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Nanobiophotonics and Biomedical Applications III",
note = "Nanobiophotonics and Biomedical Applications III ; Conference date: 23-01-2006 Through 24-01-2006",
}