Cloning the gene encoding Schistosoma mansoni p50, an immunophilin

David Kiang; Amr M. Karim; Philip T. LoVerde

doi:10.1016/0378-1119(95)00829-2

Cloning the gene encoding Schistosoma mansoni p50, an immunophilin

David Kiang
, Amr M. Karim
, Philip T. LoVerde

Microbiology and Immunology

SUNY Buffalo
Ain Shams University

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A 2.2-kb fragment of genomic DNA encoding Schistosoma mansoni immunophilin p50 (Smp50) was identified on a 14-kb genomic clone. The sequence of Smp50 reveals seven exons interrupted by six small introns ranging from 28-35 bp in size. The transcription start point, defined by primer extension analysis of schistosome RNA, begins at 30 bp upstream from the start AUG codon. Smp50 lacks a TATA box and appears to be a single-copy gene.

Original language	English
Pages (from-to)	137-140
Number of pages	4
Journal	Gene
Volume	170
Issue number	1
DOIs	https://doi.org/10.1016/0378-1119(95)00829-2
State	Published - Apr 17 1996

Keywords

FK506-binding protein
p59 protein family

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10.1016/0378-1119(95)00829-2

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title = "Cloning the gene encoding Schistosoma mansoni p50, an immunophilin",

abstract = "A 2.2-kb fragment of genomic DNA encoding Schistosoma mansoni immunophilin p50 (Smp50) was identified on a 14-kb genomic clone. The sequence of Smp50 reveals seven exons interrupted by six small introns ranging from 28-35 bp in size. The transcription start point, defined by primer extension analysis of schistosome RNA, begins at 30 bp upstream from the start AUG codon. Smp50 lacks a TATA box and appears to be a single-copy gene.",

keywords = "FK506-binding protein, p59 protein family",

author = "David Kiang and Karim, \{Amr M.\} and LoVerde, \{Philip T.\}",

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T1 - Cloning the gene encoding Schistosoma mansoni p50, an immunophilin

AU - Kiang, David

AU - Karim, Amr M.

AU - LoVerde, Philip T.

PY - 1996/4/17

Y1 - 1996/4/17

N2 - A 2.2-kb fragment of genomic DNA encoding Schistosoma mansoni immunophilin p50 (Smp50) was identified on a 14-kb genomic clone. The sequence of Smp50 reveals seven exons interrupted by six small introns ranging from 28-35 bp in size. The transcription start point, defined by primer extension analysis of schistosome RNA, begins at 30 bp upstream from the start AUG codon. Smp50 lacks a TATA box and appears to be a single-copy gene.

AB - A 2.2-kb fragment of genomic DNA encoding Schistosoma mansoni immunophilin p50 (Smp50) was identified on a 14-kb genomic clone. The sequence of Smp50 reveals seven exons interrupted by six small introns ranging from 28-35 bp in size. The transcription start point, defined by primer extension analysis of schistosome RNA, begins at 30 bp upstream from the start AUG codon. Smp50 lacks a TATA box and appears to be a single-copy gene.

KW - FK506-binding protein

KW - p59 protein family

UR - https://www.scopus.com/pages/publications/0029935659

U2 - 10.1016/0378-1119(95)00829-2

DO - 10.1016/0378-1119(95)00829-2

M3 - Article

C2 - 8621074

AN - SCOPUS:0029935659

SN - 0378-1119

VL - 170

SP - 137

EP - 140

JO - Gene

JF - Gene

IS - 1

ER -

Cloning the gene encoding Schistosoma mansoni p50, an immunophilin

Abstract

Keywords

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