Clinical variables and hypothalamic-pituitary-adrenal function in depression. The importance of mood reactivity

Carmen Z. Lemus; Gregory M. Asnis; Uriel Halbreich; Jill M. Harkavy Friedman; Herman M. Van Praag; Eileen Rubinson; Jacques Eisenberg

doi:10.1016/0165-0327(87)90030-9

Clinical variables and hypothalamic-pituitary-adrenal function in depression. The importance of mood reactivity

Carmen Z. Lemus
, Gregory M. Asnis
, Uriel Halbreich
, Jill M. Harkavy Friedman
, Herman M. Van Praag
, Eileen Rubinson
, Jacques Eisenberg

Department of Psychiatry

Albert Einstein College of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Forty outpatients with major depressive disorder were studied with the 1 mg DST and the Afternoon Cortisol Test. No relationship was found between hypothalamic-pituitary-adrenal (HPA) axis function and Research Diagnostic Criteria subtypes of depression, with the exception of higher log post-dexamethasone cortisol levels in endogeneous depressives. Patients with mood reactivity had lower cortisol values on all assessments. The data suggest that the presence of mood reactivity may be useful as a predictor of normal HPA function in depression.

Original language	English
Pages (from-to)	219-221
Number of pages	3
Journal	Journal of Affective Disorders
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/0165-0327(87)90030-9
State	Published - 1987

Keywords

(Afternoon Cortisol Test)
Cortisol values
Depression
Hypothalamic-pituitary-adrenal (HPA) axis function
Mood reactivity

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10.1016/0165-0327(87)90030-9

Cite this

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title = "Clinical variables and hypothalamic-pituitary-adrenal function in depression. The importance of mood reactivity",

abstract = "Forty outpatients with major depressive disorder were studied with the 1 mg DST and the Afternoon Cortisol Test. No relationship was found between hypothalamic-pituitary-adrenal (HPA) axis function and Research Diagnostic Criteria subtypes of depression, with the exception of higher log post-dexamethasone cortisol levels in endogeneous depressives. Patients with mood reactivity had lower cortisol values on all assessments. The data suggest that the presence of mood reactivity may be useful as a predictor of normal HPA function in depression.",

keywords = "(Afternoon Cortisol Test), Cortisol values, Depression, Hypothalamic-pituitary-adrenal (HPA) axis function, Mood reactivity",

author = "Lemus, \{Carmen Z.\} and Asnis, \{Gregory M.\} and Uriel Halbreich and \{Harkavy Friedman\}, \{Jill M.\} and \{Van Praag\}, \{Herman M.\} and Eileen Rubinson and Jacques Eisenberg",

year = "1987",

doi = "10.1016/0165-0327(87)90030-9",

language = "English",

volume = "12",

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T1 - Clinical variables and hypothalamic-pituitary-adrenal function in depression. The importance of mood reactivity

AU - Lemus, Carmen Z.

AU - Asnis, Gregory M.

AU - Halbreich, Uriel

AU - Harkavy Friedman, Jill M.

AU - Van Praag, Herman M.

AU - Rubinson, Eileen

AU - Eisenberg, Jacques

PY - 1987

Y1 - 1987

N2 - Forty outpatients with major depressive disorder were studied with the 1 mg DST and the Afternoon Cortisol Test. No relationship was found between hypothalamic-pituitary-adrenal (HPA) axis function and Research Diagnostic Criteria subtypes of depression, with the exception of higher log post-dexamethasone cortisol levels in endogeneous depressives. Patients with mood reactivity had lower cortisol values on all assessments. The data suggest that the presence of mood reactivity may be useful as a predictor of normal HPA function in depression.

AB - Forty outpatients with major depressive disorder were studied with the 1 mg DST and the Afternoon Cortisol Test. No relationship was found between hypothalamic-pituitary-adrenal (HPA) axis function and Research Diagnostic Criteria subtypes of depression, with the exception of higher log post-dexamethasone cortisol levels in endogeneous depressives. Patients with mood reactivity had lower cortisol values on all assessments. The data suggest that the presence of mood reactivity may be useful as a predictor of normal HPA function in depression.

KW - (Afternoon Cortisol Test)

KW - Cortisol values

KW - Depression

KW - Hypothalamic-pituitary-adrenal (HPA) axis function

KW - Mood reactivity

UR - https://www.scopus.com/pages/publications/0023190544

U2 - 10.1016/0165-0327(87)90030-9

DO - 10.1016/0165-0327(87)90030-9

M3 - Article

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AN - SCOPUS:0023190544

SN - 0165-0327

VL - 12

SP - 219

EP - 221

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

IS - 3

ER -

Clinical variables and hypothalamic-pituitary-adrenal function in depression. The importance of mood reactivity

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Keywords

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