Clicking well-defined biodegradable nanoparticles and nanocapsules by UV-induced thiol-ene cross-linking in transparent miniemulsions

Jiong Zou; Chyi Chin Hew; Efrosyni Themistou; Yukun Li; Chih Kuang Chen; Paschalis Alexandridis; Chong Cheng

doi:10.1002/adma.201101646

Clicking well-defined biodegradable nanoparticles and nanocapsules by UV-induced thiol-ene cross-linking in transparent miniemulsions

Jiong Zou
, Chyi Chin Hew
, Efrosyni Themistou
, Yukun Li
, Chih Kuang Chen
, Paschalis Alexandridis
, Chong Cheng

Department of Chemical and Biological Engineering

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

A novel approach for the preparation of nanomaterials is developed by tuning miniemulsion reaction systems to be transparent in order to enable highly efficient photoreactions. Biodegradable nanoparticles and nanocapsules are obtained by UV-induced thiol-ene cross-linking of polylactide (PLA)-based precursor polymers preassembled in transparent miniemulsions. These well-defined nanomaterials may potentially serve as ideal scaffolds for drug delivery.

Original language	English
Pages (from-to)	4274-4277
Number of pages	4
Journal	Advanced Materials
Volume	23
Issue number	37
DOIs	https://doi.org/10.1002/adma.201101646
State	Published - Oct 4 2011

Keywords

biodegradable nanoparticles
miniemulsions
nanocapsules
thiol-ene reaction

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10.1002/adma.201101646

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abstract = "A novel approach for the preparation of nanomaterials is developed by tuning miniemulsion reaction systems to be transparent in order to enable highly efficient photoreactions. Biodegradable nanoparticles and nanocapsules are obtained by UV-induced thiol-ene cross-linking of polylactide (PLA)-based precursor polymers preassembled in transparent miniemulsions. These well-defined nanomaterials may potentially serve as ideal scaffolds for drug delivery.",

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author = "Jiong Zou and Hew, \{Chyi Chin\} and Efrosyni Themistou and Yukun Li and Chen, \{Chih Kuang\} and Paschalis Alexandridis and Chong Cheng",

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AU - Zou, Jiong

AU - Hew, Chyi Chin

AU - Themistou, Efrosyni

AU - Li, Yukun

AU - Chen, Chih Kuang

AU - Alexandridis, Paschalis

AU - Cheng, Chong

PY - 2011/10/4

Y1 - 2011/10/4

N2 - A novel approach for the preparation of nanomaterials is developed by tuning miniemulsion reaction systems to be transparent in order to enable highly efficient photoreactions. Biodegradable nanoparticles and nanocapsules are obtained by UV-induced thiol-ene cross-linking of polylactide (PLA)-based precursor polymers preassembled in transparent miniemulsions. These well-defined nanomaterials may potentially serve as ideal scaffolds for drug delivery.

AB - A novel approach for the preparation of nanomaterials is developed by tuning miniemulsion reaction systems to be transparent in order to enable highly efficient photoreactions. Biodegradable nanoparticles and nanocapsules are obtained by UV-induced thiol-ene cross-linking of polylactide (PLA)-based precursor polymers preassembled in transparent miniemulsions. These well-defined nanomaterials may potentially serve as ideal scaffolds for drug delivery.

KW - biodegradable nanoparticles

KW - miniemulsions

KW - nanocapsules

KW - thiol-ene reaction

UR - https://www.scopus.com/pages/publications/80054697015

U2 - 10.1002/adma.201101646

DO - 10.1002/adma.201101646

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JO - Advanced Materials

JF - Advanced Materials

IS - 37

ER -

Clicking well-defined biodegradable nanoparticles and nanocapsules by UV-induced thiol-ene cross-linking in transparent miniemulsions

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Keywords

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