CistromeMap: A knowledgebase and web server for ChIP-Seq and DNase-Seq studies in mouse and human

Bo Qin; Meng Zhou; Ying Ge; Len Taing; Tao Liu; Qian Wang; Su Wang; Junsheng Chen; Lingling Shen; Xikun Duan; Sheng'en Hu; Wei Li; Henry Long; Yong Zhang; X. Shirley Liu

doi:10.1093/bioinformatics/bts157

CistromeMap: A knowledgebase and web server for ChIP-Seq and DNase-Seq studies in mouse and human

Bo Qin
, Meng Zhou
, Ying Ge
, Len Taing
, Tao Liu
, Qian Wang
, Su Wang
, Junsheng Chen
, Lingling Shen
, Xikun Duan
, Sheng'en Hu
, Wei Li
, Henry Long
, Yong Zhang
, X. Shirley Liu

Biochemistry

Tongji University
University of Southern California
Dana-Farber Cancer Institute
Harvard University
Novartis
Baylor College of Medicine

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Transcription and chromatin regulators, and histone modifications play essential roles in gene expression regulation. We have created CistromeMap as a web server to provide a comprehensive knowledgebase of all of the publicly available ChIPSeq and DNase-Seq data in mouse and human. We have also manually curated metadata to ensure annotation consistency, and developed a user-friendly display matrix for quick navigation and retrieval of data for specific factors, cells and papers. Finally, we provide users with summary statistics of ChIP-Seq and DNase-Seq studies.

Original language	English
Article number	bts157
Pages (from-to)	1411-1412
Number of pages	2
Journal	Bioinformatics
Volume	28
Issue number	10
DOIs	https://doi.org/10.1093/bioinformatics/bts157
State	Published - May 2012

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10.1093/bioinformatics/bts157

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abstract = "Transcription and chromatin regulators, and histone modifications play essential roles in gene expression regulation. We have created CistromeMap as a web server to provide a comprehensive knowledgebase of all of the publicly available ChIPSeq and DNase-Seq data in mouse and human. We have also manually curated metadata to ensure annotation consistency, and developed a user-friendly display matrix for quick navigation and retrieval of data for specific factors, cells and papers. Finally, we provide users with summary statistics of ChIP-Seq and DNase-Seq studies.",

author = "Bo Qin and Meng Zhou and Ying Ge and Len Taing and Tao Liu and Qian Wang and Su Wang and Junsheng Chen and Lingling Shen and Xikun Duan and Sheng'en Hu and Wei Li and Henry Long and Yong Zhang and Liu, \{X. Shirley\}",

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AU - Qin, Bo

AU - Zhou, Meng

AU - Ge, Ying

AU - Taing, Len

AU - Liu, Tao

AU - Wang, Qian

AU - Wang, Su

AU - Chen, Junsheng

AU - Shen, Lingling

AU - Duan, Xikun

AU - Hu, Sheng'en

AU - Li, Wei

AU - Long, Henry

AU - Zhang, Yong

AU - Liu, X. Shirley

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AB - Transcription and chromatin regulators, and histone modifications play essential roles in gene expression regulation. We have created CistromeMap as a web server to provide a comprehensive knowledgebase of all of the publicly available ChIPSeq and DNase-Seq data in mouse and human. We have also manually curated metadata to ensure annotation consistency, and developed a user-friendly display matrix for quick navigation and retrieval of data for specific factors, cells and papers. Finally, we provide users with summary statistics of ChIP-Seq and DNase-Seq studies.

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JF - Bioinformatics

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ER -

CistromeMap: A knowledgebase and web server for ChIP-Seq and DNase-Seq studies in mouse and human

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