Skip to main navigation Skip to search Skip to main content

Chronic Tubulointerstitial Nephritis Presenting as Multiple Renal Nodules and Pancreatic Insufficiency

  • University of Pennsylvania

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

We report a case of chronic tubulointerstitial nephritis associated with multiple nodular lesions of the kidneys in a patient with autoimmune pancreatitis. Serum immunoglobulin G4 (IgG4) level was increased, and immunohistochemical staining for IgG4 on the renal biopsy specimen showed positive staining of plasma cells and tubular basement membrane within areas of chronic tubulointerstitial nephritis. There are a few reports of nodular lesions of kidneys or interstitial nephritis associated with autoimmune pancreatitis. Our case is unique in that all 3 conditions presented together and suggests that interstitial nephritis can present as nodular lesions.

Original languageEnglish
Pages (from-to)e7-e10
JournalAmerican Journal of Kidney Diseases
Volume49
Issue number1
DOIs
StatePublished - Jan 2007

Keywords

  • autoimmune pancreatitis
  • immunoglobulin G4
  • Tubulointerstitial nephritis (TIN)

Fingerprint

Dive into the research topics of 'Chronic Tubulointerstitial Nephritis Presenting as Multiple Renal Nodules and Pancreatic Insufficiency'. Together they form a unique fingerprint.

Cite this