Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates

Ronald Kluger; Khashavar Karimian; Gerald Gish; Walter A. Pangborn; George T. Detitta

doi:10.1021/ja00236a070

Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates

Ronald Kluger
, Khashavar Karimian
, Gerald Gish
, Walter A. Pangborn
, George T. Detitta

Department of Structural Biology

University of Toronto
University of Tehran

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Original language	English
Pages (from-to)	618-620
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	109
Issue number	2
DOIs	https://doi.org/10.1021/ja00236a070
State	Published - Jan 1 1987

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Kluger, R., Karimian, K., Gish, G., Pangborn, W. A., & Detitta, G. T. (1987). Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates. Journal of the American Chemical Society, 109(2), 618-620. https://doi.org/10.1021/ja00236a070

Kluger, Ronald ; Karimian, Khashavar ; Gish, Gerald et al. / Chirality of Intermediates in Thiamin Catalysis : Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates. In: Journal of the American Chemical Society. 1987 ; Vol. 109, No. 2. pp. 618-620.

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title = "Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates",

author = "Ronald Kluger and Khashavar Karimian and Gerald Gish and Pangborn, \{Walter A.\} and Detitta, \{George T.\}",

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Kluger, R, Karimian, K, Gish, G, Pangborn, WA & Detitta, GT 1987, 'Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates', Journal of the American Chemical Society, vol. 109, no. 2, pp. 618-620. https://doi.org/10.1021/ja00236a070

Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates. / Kluger, Ronald; Karimian, Khashavar; Gish, Gerald et al.
In: Journal of the American Chemical Society, Vol. 109, No. 2, 01.01.1987, p. 618-620.

Research output: Contribution to journal › Article › peer-review

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AU - Kluger, Ronald

AU - Karimian, Khashavar

AU - Gish, Gerald

AU - Pangborn, Walter A.

AU - Detitta, George T.

PY - 1987/1/1

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DO - 10.1021/ja00236a070

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Kluger R, Karimian K, Gish G, Pangborn WA, Detitta GT. Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates. Journal of the American Chemical Society. 1987 Jan 1;109(2):618-620. doi: 10.1021/ja00236a070

Chirality of Intermediates in Thiamin Catalysis: Structure of (+)-2-(l-Hydroxyethyl)-3,4-dimethyl-5-(2-hydroxyethyl)thiazolium Iodide, the Absolute Stereochemistry of the Enantiomers of 2-(l-Hydroxyethyl)thiamin, and Enzymic Reaction of the Diphosphates

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