Characteristics of lymphocyte and macrophage reactivity in otitis media with effusion

Joel M. Bernstein; Tatsuru Yamanaka; James Cumella; Pearay L. Ogra

doi:10.3109/00016488409122894

Characteristics of lymphocyte and macrophage reactivity in otitis media with effusion

Joel M. Bernstein
, Tatsuru Yamanaka
, James Cumella
, Pearay L. Ogra

Department of Otolaryngology

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

On the basis of our observations and previously published data, it is proposed that in at least certain forms of chronic otitis media with effusion there is a relative predominance of macrophage-monocyte cells which are actively immunosuppressive for the proliferative response to mitogens and specific antigens, as well as for the synthesis of specific immunoglobulins. Such immunological hypo-responsiveness may be related to the patho-genesis of chronic otitis media with such effusions.

Original language	English
Pages (from-to)	131-137
Number of pages	7
Journal	Acta Oto-Laryngologica
Volume	98
Issue number	S418
DOIs	https://doi.org/10.3109/00016488409122894
State	Published - 1984

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title = "Characteristics of lymphocyte and macrophage reactivity in otitis media with effusion",

abstract = "On the basis of our observations and previously published data, it is proposed that in at least certain forms of chronic otitis media with effusion there is a relative predominance of macrophage-monocyte cells which are actively immunosuppressive for the proliferative response to mitogens and specific antigens, as well as for the synthesis of specific immunoglobulins. Such immunological hypo-responsiveness may be related to the patho-genesis of chronic otitis media with such effusions.",

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AU - Yamanaka, Tatsuru

AU - Cumella, James

AU - Ogra, Pearay L.

PY - 1984

Y1 - 1984

N2 - On the basis of our observations and previously published data, it is proposed that in at least certain forms of chronic otitis media with effusion there is a relative predominance of macrophage-monocyte cells which are actively immunosuppressive for the proliferative response to mitogens and specific antigens, as well as for the synthesis of specific immunoglobulins. Such immunological hypo-responsiveness may be related to the patho-genesis of chronic otitis media with such effusions.

AB - On the basis of our observations and previously published data, it is proposed that in at least certain forms of chronic otitis media with effusion there is a relative predominance of macrophage-monocyte cells which are actively immunosuppressive for the proliferative response to mitogens and specific antigens, as well as for the synthesis of specific immunoglobulins. Such immunological hypo-responsiveness may be related to the patho-genesis of chronic otitis media with such effusions.

UR - https://www.scopus.com/pages/publications/0021697298

U2 - 10.3109/00016488409122894

DO - 10.3109/00016488409122894

M3 - Article

C2 - 6241976

AN - SCOPUS:0021697298

SN - 0001-6489

VL - 98

SP - 131

EP - 137

JO - Acta Oto-Laryngologica

JF - Acta Oto-Laryngologica

IS - S418

ER -

Characteristics of lymphocyte and macrophage reactivity in otitis media with effusion

Abstract

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