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Cellular effects of serotonin in the CNS

  • Wayne State University

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Serotonergic neurons innervate the entire neuroaxis thus allowing serotonin to regulate the function of most CNS neurons. Work during the last 2 decades has made clear that the specific form taken by this regulation is dependent on the complement of serotonin receptors expressed by each cell. This general principle is now being extended to different cell types within defined neuronal networks to understand how serotonin regulates network function. In this chapter, we review progress along this front in two intensely studied areas, the hippocampus and the cerebral cortex, and highlight areas of progress while noting outstanding issues that await elucidation.

Original languageEnglish
Title of host publicationHandbook of Behavioral Neuroscience
PublisherElsevier B.V.
Pages279-288
Number of pages10
DOIs
StatePublished - 2020

Publication series

NameHandbook of Behavioral Neuroscience
Volume31
ISSN (Print)1569-7339

Keywords

  • 5-HT
  • 5-HT
  • 5-HT
  • 5-HT
  • 5-HT
  • 5-HT
  • 5-HT6
  • Cortex
  • GABAergic interneurons
  • Hippocampus
  • Pyramidal neurons
  • Serotonin

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