Cardiovascular system

Nita Doshi; Vivian I. Franco; Anthony C. Chang; Steven E. Lipshultz

doi:10.1007/978-1-4899-7584-3_7

Cardiovascular system

Nita Doshi
, Vivian I. Franco
, Anthony C. Chang
, Steven E. Lipshultz

Pediatrics

University of California at Irvine
University of Miami

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Cardiotoxicity is a late effect of pediatric cancer and its treatment that increases the risk of morbidity and mortality. This may result from a variety of antineoplastic therapies, including independent or combined effects of chemotherapy and radiation therapy. Late cardiotoxicity following anthracycline therapy is mostly subclinical, often progressive, potentially severe, and sometimes fatal. Therefore risk-based surveillance is extremely important in caring for survivors. This chapter discusses the pathophysiology, risk factors, late effects, screening recommendations as well as ongoing research in the field of Onco-Cardiology.

Original language	English
Title of host publication	Handbook of Long Term Care of The Childhood Cancer Survivor
Publisher	Springer US
Pages	93-110
Number of pages	18
ISBN (Electronic)	9781489975843
ISBN (Print)	9781489975836
DOIs	https://doi.org/10.1007/978-1-4899-7584-3_7
State	Published - Jan 1 2015

Keywords

Anthracyclines
Cardiac biomarkers
Cardiomyopathyn
Radiation
Screening guidelines

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10.1007/978-1-4899-7584-3_7

Cite this

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abstract = "Cardiotoxicity is a late effect of pediatric cancer and its treatment that increases the risk of morbidity and mortality. This may result from a variety of antineoplastic therapies, including independent or combined effects of chemotherapy and radiation therapy. Late cardiotoxicity following anthracycline therapy is mostly subclinical, often progressive, potentially severe, and sometimes fatal. Therefore risk-based surveillance is extremely important in caring for survivors. This chapter discusses the pathophysiology, risk factors, late effects, screening recommendations as well as ongoing research in the field of Onco-Cardiology.",

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T1 - Cardiovascular system

AU - Doshi, Nita

AU - Franco, Vivian I.

AU - Chang, Anthony C.

AU - Lipshultz, Steven E.

N1 - Publisher Copyright: © Springer Science+Business Media New York 2015.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Cardiotoxicity is a late effect of pediatric cancer and its treatment that increases the risk of morbidity and mortality. This may result from a variety of antineoplastic therapies, including independent or combined effects of chemotherapy and radiation therapy. Late cardiotoxicity following anthracycline therapy is mostly subclinical, often progressive, potentially severe, and sometimes fatal. Therefore risk-based surveillance is extremely important in caring for survivors. This chapter discusses the pathophysiology, risk factors, late effects, screening recommendations as well as ongoing research in the field of Onco-Cardiology.

AB - Cardiotoxicity is a late effect of pediatric cancer and its treatment that increases the risk of morbidity and mortality. This may result from a variety of antineoplastic therapies, including independent or combined effects of chemotherapy and radiation therapy. Late cardiotoxicity following anthracycline therapy is mostly subclinical, often progressive, potentially severe, and sometimes fatal. Therefore risk-based surveillance is extremely important in caring for survivors. This chapter discusses the pathophysiology, risk factors, late effects, screening recommendations as well as ongoing research in the field of Onco-Cardiology.

KW - Anthracyclines

KW - Cardiac biomarkers

KW - Cardiomyopathyn

KW - Radiation

KW - Screening guidelines

UR - https://www.scopus.com/pages/publications/84944518621

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DO - 10.1007/978-1-4899-7584-3_7

M3 - Chapter

AN - SCOPUS:84944518621

SN - 9781489975836

SP - 93

EP - 110

BT - Handbook of Long Term Care of The Childhood Cancer Survivor

PB - Springer US

ER -

Cardiovascular system

Abstract

Keywords

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