Breastfeeding and maternal alcohol use: Prevalence and effects on child outcomes and fetal alcohol spectrum disorders

Philip A. May; Julie M. Hasken; Jason Blankenship; Anna Susan Marais; Belinda Joubert; Marise Cloete; Marlene M. de Vries; Ronel Barnard; Isobel Botha; Sumien Roux; Cate Doms; J. Phillip Gossage; Wendy O. Kalberg; David Buckley; Luther K. Robinson; Colleen M. Adnams; Melanie A. Manning; Charles D.H. Parry; H. Eugene Hoyme; Barbara Tabachnick; Soraya Seedat

doi:10.1016/j.reprotox.2016.05.002

Breastfeeding and maternal alcohol use: Prevalence and effects on child outcomes and fetal alcohol spectrum disorders

Philip A. May
, Julie M. Hasken
, Jason Blankenship
, Anna Susan Marais
, Belinda Joubert
, Marise Cloete
, Marlene M. de Vries
, Ronel Barnard
, Isobel Botha
, Sumien Roux
, Cate Doms
, J. Phillip Gossage
, Wendy O. Kalberg
, David Buckley
, Luther K. Robinson
, Colleen M. Adnams
, Melanie A. Manning
, Charles D.H. Parry
, H. Eugene Hoyme
, Barbara Tabachnick

Soraya Seedat

Pediatrics

University of North Carolina at Chapel Hill
University of New Mexico
Stellenbosch University
University of Cape Town
Stanford University
South African Medical Research Council
University of South Dakota
California State University Northridge

Research output: Contribution to journal › Article › peer-review

74 Scopus citations

Abstract

Objective: Determine any effects that maternal alcohol consumption during the breastfeeding period has on child outcomes. Methods: Population-based samples of children with fetal alcohol spectrum disorders (FASD), normally-developing children, and their mothers were analyzed for differences in child outcomes. Results: Ninety percent (90%) of mothers breastfed for an average of 19.9 months. Of mothers who drank postpartum and breastfed (MDPB), 47% breastfed for 12 months or more. In case control analyses, children of MDPB were significantly lighter, had lower verbal IQ scores, and more anomalies in comparisons controlling for prenatal alcohol exposure and final FASD diagnosis. Utilizing a stepwise logistic regression model adjusting for nine confounders of prenatal drinking and other maternal risks, MDPB were 6.4 times more likely to have a child with FASD than breastfeeding mothers who abstained from alcohol while breastfeeding. Conclusions: Alcohol use during the period of breastfeeding was found to significantly compromise a child's development.

Original language	English
Pages (from-to)	13-21
Number of pages	9
Journal	Reproductive Toxicology
Volume	63
DOIs	https://doi.org/10.1016/j.reprotox.2016.05.002
State	Published - Aug 1 2016

Keywords

Alcohol
Breastfeeding
Child health and development
Fetal alcohol spectrum disorders (FASD)
Pregnancy

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10.1016/j.reprotox.2016.05.002

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May, P. A., Hasken, J. M., Blankenship, J., Marais, A. S., Joubert, B., Cloete, M., de Vries, M. M., Barnard, R., Botha, I., Roux, S., Doms, C., Gossage, J. P., Kalberg, W. O., Buckley, D., Robinson, L. K., Adnams, C. M., Manning, M. A., Parry, C. D. H., Hoyme, H. E., ... Seedat, S. (2016). Breastfeeding and maternal alcohol use: Prevalence and effects on child outcomes and fetal alcohol spectrum disorders. Reproductive Toxicology, 63, 13-21. https://doi.org/10.1016/j.reprotox.2016.05.002

@article{2eecc7562ee2426bb5cf0cbd92c24239,

title = "Breastfeeding and maternal alcohol use: Prevalence and effects on child outcomes and fetal alcohol spectrum disorders",

abstract = "Objective: Determine any effects that maternal alcohol consumption during the breastfeeding period has on child outcomes. Methods: Population-based samples of children with fetal alcohol spectrum disorders (FASD), normally-developing children, and their mothers were analyzed for differences in child outcomes. Results: Ninety percent (90\%) of mothers breastfed for an average of 19.9 months. Of mothers who drank postpartum and breastfed (MDPB), 47\% breastfed for 12 months or more. In case control analyses, children of MDPB were significantly lighter, had lower verbal IQ scores, and more anomalies in comparisons controlling for prenatal alcohol exposure and final FASD diagnosis. Utilizing a stepwise logistic regression model adjusting for nine confounders of prenatal drinking and other maternal risks, MDPB were 6.4 times more likely to have a child with FASD than breastfeeding mothers who abstained from alcohol while breastfeeding. Conclusions: Alcohol use during the period of breastfeeding was found to significantly compromise a child's development.",

keywords = "Alcohol, Breastfeeding, Child health and development, Fetal alcohol spectrum disorders (FASD), Pregnancy",

author = "May, \{Philip A.\} and Hasken, \{Julie M.\} and Jason Blankenship and Marais, \{Anna Susan\} and Belinda Joubert and Marise Cloete and \{de Vries\}, \{Marlene M.\} and Ronel Barnard and Isobel Botha and Sumien Roux and Cate Doms and Gossage, \{J. Phillip\} and Kalberg, \{Wendy O.\} and David Buckley and Robinson, \{Luther K.\} and Adnams, \{Colleen M.\} and Manning, \{Melanie A.\} and Parry, \{Charles D.H.\} and Hoyme, \{H. Eugene\} and Barbara Tabachnick and Soraya Seedat",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = aug,

day = "1",

doi = "10.1016/j.reprotox.2016.05.002",

language = "English",

volume = "63",

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May, PA, Hasken, JM, Blankenship, J, Marais, AS, Joubert, B, Cloete, M, de Vries, MM, Barnard, R, Botha, I, Roux, S, Doms, C, Gossage, JP, Kalberg, WO, Buckley, D, Robinson, LK, Adnams, CM, Manning, MA, Parry, CDH, Hoyme, HE, Tabachnick, B & Seedat, S 2016, 'Breastfeeding and maternal alcohol use: Prevalence and effects on child outcomes and fetal alcohol spectrum disorders', Reproductive Toxicology, vol. 63, pp. 13-21. https://doi.org/10.1016/j.reprotox.2016.05.002

TY - JOUR

T1 - Breastfeeding and maternal alcohol use

T2 - Prevalence and effects on child outcomes and fetal alcohol spectrum disorders

AU - May, Philip A.

AU - Hasken, Julie M.

AU - Blankenship, Jason

AU - Marais, Anna Susan

AU - Joubert, Belinda

AU - Cloete, Marise

AU - de Vries, Marlene M.

AU - Barnard, Ronel

AU - Botha, Isobel

AU - Roux, Sumien

AU - Doms, Cate

AU - Gossage, J. Phillip

AU - Kalberg, Wendy O.

AU - Buckley, David

AU - Robinson, Luther K.

AU - Adnams, Colleen M.

AU - Manning, Melanie A.

AU - Parry, Charles D.H.

AU - Hoyme, H. Eugene

AU - Tabachnick, Barbara

AU - Seedat, Soraya

PY - 2016/8/1

Y1 - 2016/8/1

N2 - Objective: Determine any effects that maternal alcohol consumption during the breastfeeding period has on child outcomes. Methods: Population-based samples of children with fetal alcohol spectrum disorders (FASD), normally-developing children, and their mothers were analyzed for differences in child outcomes. Results: Ninety percent (90%) of mothers breastfed for an average of 19.9 months. Of mothers who drank postpartum and breastfed (MDPB), 47% breastfed for 12 months or more. In case control analyses, children of MDPB were significantly lighter, had lower verbal IQ scores, and more anomalies in comparisons controlling for prenatal alcohol exposure and final FASD diagnosis. Utilizing a stepwise logistic regression model adjusting for nine confounders of prenatal drinking and other maternal risks, MDPB were 6.4 times more likely to have a child with FASD than breastfeeding mothers who abstained from alcohol while breastfeeding. Conclusions: Alcohol use during the period of breastfeeding was found to significantly compromise a child's development.

AB - Objective: Determine any effects that maternal alcohol consumption during the breastfeeding period has on child outcomes. Methods: Population-based samples of children with fetal alcohol spectrum disorders (FASD), normally-developing children, and their mothers were analyzed for differences in child outcomes. Results: Ninety percent (90%) of mothers breastfed for an average of 19.9 months. Of mothers who drank postpartum and breastfed (MDPB), 47% breastfed for 12 months or more. In case control analyses, children of MDPB were significantly lighter, had lower verbal IQ scores, and more anomalies in comparisons controlling for prenatal alcohol exposure and final FASD diagnosis. Utilizing a stepwise logistic regression model adjusting for nine confounders of prenatal drinking and other maternal risks, MDPB were 6.4 times more likely to have a child with FASD than breastfeeding mothers who abstained from alcohol while breastfeeding. Conclusions: Alcohol use during the period of breastfeeding was found to significantly compromise a child's development.

KW - Alcohol

KW - Breastfeeding

KW - Child health and development

KW - Fetal alcohol spectrum disorders (FASD)

KW - Pregnancy

UR - https://www.scopus.com/pages/publications/84969256414

U2 - 10.1016/j.reprotox.2016.05.002

DO - 10.1016/j.reprotox.2016.05.002

M3 - Article

C2 - 27174445

AN - SCOPUS:84969256414

SN - 0890-6238

VL - 63

SP - 13

EP - 21

JO - Reproductive Toxicology

JF - Reproductive Toxicology

ER -

Breastfeeding and maternal alcohol use: Prevalence and effects on child outcomes and fetal alcohol spectrum disorders

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Keywords

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