Brain Tumors in Infants

Derek Jenkin; James C. Longcope; Sue S. Watson; Patricia K. Duffner; Jeffrey C. Allen; Larry E. Kun

doi:10.1056/NEJM199312233292614

Brain Tumors in Infants

Derek Jenkin
, James C. Longcope
, Sue S. Watson
, Patricia K. Duffner
, Jeffrey C. Allen
, Larry E. Kun

Neurology

University of Toronto
Millbrook Psychiatric Services
New York University
St. Jude Children Research Hospital

Research output: Contribution to journal › Letter › peer-review

1 Scopus citations

Abstract

To the Editor: The treatment of infants with malignant brain tumors by maximal resection and chemotherapy, with radiation treatment delayed to the age of 24 to 48 months (June 17 issue),¹ is an important new strategy with the objective of decreasing morbidity due to radiation. For this objective to be attained, it is necessary to demonstrate that survival is not decreased and that the early and late toxic effects of systemic therapy are less than the incremental toxic effects associated with radiation treatment at an earlier age. Since the study did not have control subjects, the authors sought assurance that…

Original language	English
Pages (from-to)	1963-1964
Number of pages	2
Journal	New England Journal of Medicine
Volume	329
Issue number	26
DOIs	https://doi.org/10.1056/NEJM199312233292614
State	Published - Dec 23 1993

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title = "Brain Tumors in Infants",

abstract = "To the Editor: The treatment of infants with malignant brain tumors by maximal resection and chemotherapy, with radiation treatment delayed to the age of 24 to 48 months (June 17 issue),1 is an important new strategy with the objective of decreasing morbidity due to radiation. For this objective to be attained, it is necessary to demonstrate that survival is not decreased and that the early and late toxic effects of systemic therapy are less than the incremental toxic effects associated with radiation treatment at an earlier age. Since the study did not have control subjects, the authors sought assurance that…",

author = "Derek Jenkin and Longcope, \{James C.\} and Watson, \{Sue S.\} and Duffner, \{Patricia K.\} and Allen, \{Jeffrey C.\} and Kun, \{Larry E.\}",

year = "1993",

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AU - Jenkin, Derek

AU - Longcope, James C.

AU - Watson, Sue S.

AU - Duffner, Patricia K.

AU - Allen, Jeffrey C.

AU - Kun, Larry E.

PY - 1993/12/23

Y1 - 1993/12/23

N2 - To the Editor: The treatment of infants with malignant brain tumors by maximal resection and chemotherapy, with radiation treatment delayed to the age of 24 to 48 months (June 17 issue),1 is an important new strategy with the objective of decreasing morbidity due to radiation. For this objective to be attained, it is necessary to demonstrate that survival is not decreased and that the early and late toxic effects of systemic therapy are less than the incremental toxic effects associated with radiation treatment at an earlier age. Since the study did not have control subjects, the authors sought assurance that…

AB - To the Editor: The treatment of infants with malignant brain tumors by maximal resection and chemotherapy, with radiation treatment delayed to the age of 24 to 48 months (June 17 issue),1 is an important new strategy with the objective of decreasing morbidity due to radiation. For this objective to be attained, it is necessary to demonstrate that survival is not decreased and that the early and late toxic effects of systemic therapy are less than the incremental toxic effects associated with radiation treatment at an earlier age. Since the study did not have control subjects, the authors sought assurance that…

UR - https://www.scopus.com/pages/publications/0027923047

U2 - 10.1056/NEJM199312233292614

DO - 10.1056/NEJM199312233292614

M3 - Letter

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EP - 1964

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 26

ER -

Brain Tumors in Infants

Abstract

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