Blood Pressure Response of Adrenal-Enucleated Rats to Restricted And Irregular Feeding Patterns and to Subsequent ad Libitum Realimentation

1. Restricted food intake resulted in smaller increases of blood pressure in intact as well as in adrenal-enucleated (AE) rats when compared with corresponding controls but fed ad libitum. However, AE rats showed a greater increase in blood pressure when compared with intact rats, and this holds particularly for the food-restricted groups. 2. A 10-day realimentation regimen following periods of restricted feeding resulted in greater increases of blood pressure in formerly food-restricted AE rats than in corresponding intact animals. This increase in blood pressure occurred although the AE rats did not ingest more NaCl than the ad libitum-fed AE rats and intact controls. 3. It may be concluded that the regenerating adrenal does not lose its hypertensive potential despite food and thus NaCl restriction.