Bisphosphonate-related osteonecrosis of the jaw: The role of actinomyces

Nimesh H. Naik; Thomas A. Russo

doi:10.1086/648075

Bisphosphonate-related osteonecrosis of the jaw: The role of actinomyces

Nimesh H. Naik
, Thomas A. Russo

Medicine

Department of Veterans Affairs

Research output: Contribution to journal › Article › peer-review

92 Scopus citations

Abstract

The etiology of bisphosphonate-related osteonecrosis of the jaw is unknown but was initially postulated to be mediated by bisphosphonate accumulation within the jaws, resulting in avascular necrosis. Bisphosphonates may not be the primary cause. Actinomyces are an underrecognized agent in pathogenesis, and timely actinomycosis-specific treatment may improve outcome.

Original language	English
Pages (from-to)	1729-1732
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	49
Issue number	11
DOIs	https://doi.org/10.1086/648075
State	Published - Dec 2009

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abstract = "The etiology of bisphosphonate-related osteonecrosis of the jaw is unknown but was initially postulated to be mediated by bisphosphonate accumulation within the jaws, resulting in avascular necrosis. Bisphosphonates may not be the primary cause. Actinomyces are an underrecognized agent in pathogenesis, and timely actinomycosis-specific treatment may improve outcome.",

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AU - Russo, Thomas A.

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AB - The etiology of bisphosphonate-related osteonecrosis of the jaw is unknown but was initially postulated to be mediated by bisphosphonate accumulation within the jaws, resulting in avascular necrosis. Bisphosphonates may not be the primary cause. Actinomyces are an underrecognized agent in pathogenesis, and timely actinomycosis-specific treatment may improve outcome.

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JO - Clinical Infectious Diseases

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ER -

Bisphosphonate-related osteonecrosis of the jaw: The role of actinomyces

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