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Autoradiolytic Decomposition of Reductant-free Sodium 124I- and 123I-Iodide

  • King Faisal Specialist Hospital and Research Centre

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The presence of salts and metal cations in 124I- and 123I-sodium iodide solutions separated from 124Te targets promotes autoradiolytic decomposition of iodide to several different iodine species dependent upon the chemical environment. The stabilization of the radioiodine as iodide by removal of trace salts and trace metal cations and in the absence of reducing agents is described. The high specific activity 123I- and 124I-iodide is suitable for labeling antibodies, proteins and radiopharmaceuticals.

Original languageEnglish
Pages (from-to)123-128
Number of pages6
JournalRadiochimica Acta
Volume50
Issue number1-2
DOIs
StatePublished - May 1990

Keywords

  • Autoradiolytic decomposition
  • Radioanalytical Separation
  • Radionuclides of iodine
  • Self-radiolysis
  • Stabilization of radiopharmaceuticals

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