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Association between Blood Pressure and Retinal Vessel Diameters among Police Officers in the US Northeast

  • Ja K. Gu
  • , Luenda E. Charles
  • , Ronald Klein
  • , Lisa M. Grady
  • , Claudia C. Ma
  • , Penelope Allison
  • , John M. Violanti
  • , Michael E. Andrew
  • National Institute for Occupational Safety and Health
  • University of Wisconsin-Madison

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Objective: The aim of this study was to examine relationships of blood pressure with central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) among 242 police officers. Methods: Computerized retinal images of each eye were taken. Mean values of CRAE and CRVE were compared across hypertension status categories using analysis of variance and analysis of covariance. Associations of mean arterial blood pressure (MABP) with CRAE and CRVE were obtained using regression models. Results: CRAE was significantly narrower in officers with uncontrolled hypertension (142.8 ± 2.7 μm), compared with those with controlled hypertension (153.6 ± 2.7 μm, P = 0.0013) and those with no hypertension (156.4 ± 1.0 μm, P ≤ 0.0001) after covariate adjustment. CRAE decreased by 3.43 μm for each 5 mm Hg increase in MABP (P ≤ 0.0001). Conclusion: Uncontrolled hypertension was significantly associated with narrower retinal arterioles. No association was observed with retinal venules.

Original languageEnglish
Pages (from-to)234-240
Number of pages7
JournalJournal of Occupational and Environmental Medicine
Volume60
Issue number3
DOIs
StatePublished - Mar 1 2018

Keywords

  • Abbreviations ANCOVA
  • Analysis of covariance
  • Analysis of variance
  • ANOVA
  • Cardiovascular disease
  • Central retinal arteriolar equivalent
  • Central retinal venular equivalent
  • CRAE
  • CRVE
  • CVD
  • DBP
  • Diastolic blood pressure
  • MABP
  • Mean arterial blood pressure
  • National Health and Nutrition Examination Survey
  • NHANES
  • SBP
  • Systolic blood pressure
  • WBC
  • White blood cell

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