Abstract
The applications of computer database searching and bioinformatics to characterize hexophosphotransferases were presented. The mass spectrometry (MS)/MS results of tryptic digests of bovine heart hexokinase were analyzed by DenovoX and evaluated using Sequest. The MS/MS results of tryptic peptides of rat brain hexokinase analyzed by DenovoX and evaluated by Sequesy indicated only two candidate proteins, the highest ranked matching chain A, rat brain hexokinase type I. It was observed that the number two candidate, mouse tumor hexokinase, was structurally similar, differing at 32 of the 918 residues of rat brain hexokinase.
| Original language | English |
|---|---|
| Pages | 739-740 |
| Number of pages | 2 |
| State | Published - 2002 |
| Event | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002 |
Conference
| Conference | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
|---|---|
| Country/Territory | United States |
| City | Orlando, FL |
| Period | 06/2/02 → 06/6/02 |
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