TY - GEN
T1 - Applications and challenges of real-Time mobile DNA analysis
AU - Ko, Steven Y.
AU - Sassoubre, Lauren
AU - Zola, Jaroslaw
N1 - Publisher Copyright:
© 2018 Association for Computing Machinery.
PY - 2018/2/12
Y1 - 2018/2/12
N2 - The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA sequencing outside of laboratory, leading to faster and more accessible DNA-based diagnostics. However, portable DNA sequencing and analysis are challenging for mobile systems, owing to high data throughput and computationally intensive processing performed in environments with unreliable connectivity and power. In this paper, we provide an analysis of the challenges that mobile systems must address to maximize the potential of portable DNA sequencing, and in situ DNA analysis. We explain the DNA sequencing process and highlight the main differences between traditional and portable DNA sequencing in the context of the actual and envisioned applications. We look at the identified challenges from the perspective of both algorithms and systems design, showing the need for careful co-design.
AB - The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA sequencing outside of laboratory, leading to faster and more accessible DNA-based diagnostics. However, portable DNA sequencing and analysis are challenging for mobile systems, owing to high data throughput and computationally intensive processing performed in environments with unreliable connectivity and power. In this paper, we provide an analysis of the challenges that mobile systems must address to maximize the potential of portable DNA sequencing, and in situ DNA analysis. We explain the DNA sequencing process and highlight the main differences between traditional and portable DNA sequencing in the context of the actual and envisioned applications. We look at the identified challenges from the perspective of both algorithms and systems design, showing the need for careful co-design.
KW - MinION
KW - Mobile DNA sequencing
KW - Real-Time mobile DNA analysis
UR - https://www.scopus.com/pages/publications/85048552299
U2 - 10.1145/3177102.3177114
DO - 10.1145/3177102.3177114
M3 - Conference contribution
AN - SCOPUS:85048552299
T3 - HotMobile 2018 - Proceedings of the 19th International Workshop on Mobile Computing Systems and Applications
SP - 1
EP - 6
BT - HotMobile 2018 - Proceedings of the 19th International Workshop on Mobile Computing Systems and Applications
PB - Association for Computing Machinery, Inc
T2 - 19th International Workshop on Mobile Computing Systems and Applications, HotMobile 2018
Y2 - 12 February 2018 through 13 February 2018
ER -