Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making

K. Lance Gould; Nils P. Johnson; Timothy M. Bateman; Rob S. Beanlands; Frank M. Bengel; Robert Bober; Paolo G. Camici; Manuel D. Cerqueira; Benjamin J.W. Chow; Marcelo F. Di Carli; Sharmila Dorbala; Henry Gewirtz; Robert J. Gropler; Philipp A. Kaufmann; Paul Knaapen; Juhani Knuuti; Michael E. Merhige; K. Peter Rentrop; Terrence D. Ruddy; Heinrich R. Schelbert; Thomas H. Schindler; Markus Schwaiger; Stefano Sdringola; John Vitarello; Kim A. Williams; Donald Gordon; Vasken Dilsizian; Jagat Narula

doi:10.1016/j.jacc.2013.07.076

Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making

K. Lance Gould
, Nils P. Johnson
, Timothy M. Bateman
, Rob S. Beanlands
, Frank M. Bengel
, Robert Bober
, Paolo G. Camici
, Manuel D. Cerqueira
, Benjamin J.W. Chow
, Marcelo F. Di Carli
, Sharmila Dorbala
, Henry Gewirtz
, Robert J. Gropler
, Philipp A. Kaufmann
, Paul Knaapen
, Juhani Knuuti
, Michael E. Merhige
, K. Peter Rentrop
, Terrence D. Ruddy
, Heinrich R. Schelbert

Thomas H. Schindler, Markus Schwaiger, Stefano Sdringola, John Vitarello, Kim A. Williams, Donald Gordon, Vasken Dilsizian, Jagat Narula

Nuclear Medicine

University of Texas Health Science Center at Houston
University of Missouri at Kansas City
University of Ottawa
Hannover Medical School
Ochsner Health System
Vita-Salute San Raffaele University
Cleveland Clinic Foundation
Brigham and Women’s Hospital
Massachusetts General Hospital
Washington University St. Louis
University of Zurich
VU University
University of Turku
Gramercy Cardiac Diagnostic Services
University of California at Los Angeles
University of Geneva
Technical University of Munich
Cardiovascular Specialists of Frederick
Wayne State University
Cardiovascular Associates of the Southeast
University of Maryland, Baltimore
Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Review article › peer-review

515 Scopus citations

Abstract

Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology - pressure and flow - as clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.

Original language	English
Pages (from-to)	1639-1653
Number of pages	15
Journal	Journal of the American College of Cardiology
Volume	62
Issue number	18
DOIs	https://doi.org/10.1016/j.jacc.2013.07.076
State	Published - Oct 29 2013

Keywords

coronary flow
coronary physiology
ischemia
PET perfusion imaging
revascularization

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10.1016/j.jacc.2013.07.076

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Gould, K. L., Johnson, N. P., Bateman, T. M., Beanlands, R. S., Bengel, F. M., Bober, R., Camici, P. G., Cerqueira, M. D., Chow, B. J. W., Di Carli, M. F., Dorbala, S., Gewirtz, H., Gropler, R. J., Kaufmann, P. A., Knaapen, P., Knuuti, J., Merhige, M. E., Rentrop, K. P., Ruddy, T. D., ... Narula, J. (2013). Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making. Journal of the American College of Cardiology, 62(18), 1639-1653. https://doi.org/10.1016/j.jacc.2013.07.076

@article{cd44e6d4e2ad4d41bedfb68332141956,

title = "Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making",

abstract = "Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology - pressure and flow - as clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.",

keywords = "coronary flow, coronary physiology, ischemia, PET perfusion imaging, revascularization",

author = "Gould, \{K. Lance\} and Johnson, \{Nils P.\} and Bateman, \{Timothy M.\} and Beanlands, \{Rob S.\} and Bengel, \{Frank M.\} and Robert Bober and Camici, \{Paolo G.\} and Cerqueira, \{Manuel D.\} and Chow, \{Benjamin J.W.\} and \{Di Carli\}, \{Marcelo F.\} and Sharmila Dorbala and Henry Gewirtz and Gropler, \{Robert J.\} and Kaufmann, \{Philipp A.\} and Paul Knaapen and Juhani Knuuti and Merhige, \{Michael E.\} and Rentrop, \{K. Peter\} and Ruddy, \{Terrence D.\} and Schelbert, \{Heinrich R.\} and Schindler, \{Thomas H.\} and Markus Schwaiger and Stefano Sdringola and John Vitarello and Williams, \{Kim A.\} and Donald Gordon and Vasken Dilsizian and Jagat Narula",

year = "2013",

month = oct,

day = "29",

doi = "10.1016/j.jacc.2013.07.076",

language = "English",

volume = "62",

pages = "1639--1653",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

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Gould, KL, Johnson, NP, Bateman, TM, Beanlands, RS, Bengel, FM, Bober, R, Camici, PG, Cerqueira, MD, Chow, BJW, Di Carli, MF, Dorbala, S, Gewirtz, H, Gropler, RJ, Kaufmann, PA, Knaapen, P, Knuuti, J, Merhige, ME, Rentrop, KP, Ruddy, TD, Schelbert, HR, Schindler, TH, Schwaiger, M, Sdringola, S, Vitarello, J, Williams, KA, Gordon, D, Dilsizian, V & Narula, J 2013, 'Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making', Journal of the American College of Cardiology, vol. 62, no. 18, pp. 1639-1653. https://doi.org/10.1016/j.jacc.2013.07.076

Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making. / Gould, K. Lance; Johnson, Nils P.; Bateman, Timothy M. et al.
In: Journal of the American College of Cardiology, Vol. 62, No. 18, 29.10.2013, p. 1639-1653.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Anatomic versus physiologic assessment of coronary artery disease

T2 - Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making

AU - Gould, K. Lance

AU - Johnson, Nils P.

AU - Bateman, Timothy M.

AU - Beanlands, Rob S.

AU - Bengel, Frank M.

AU - Bober, Robert

AU - Camici, Paolo G.

AU - Cerqueira, Manuel D.

AU - Chow, Benjamin J.W.

AU - Di Carli, Marcelo F.

AU - Dorbala, Sharmila

AU - Gewirtz, Henry

AU - Gropler, Robert J.

AU - Kaufmann, Philipp A.

AU - Knaapen, Paul

AU - Knuuti, Juhani

AU - Merhige, Michael E.

AU - Rentrop, K. Peter

AU - Ruddy, Terrence D.

AU - Schelbert, Heinrich R.

AU - Schindler, Thomas H.

AU - Schwaiger, Markus

AU - Sdringola, Stefano

AU - Vitarello, John

AU - Williams, Kim A.

AU - Gordon, Donald

AU - Dilsizian, Vasken

AU - Narula, Jagat

PY - 2013/10/29

Y1 - 2013/10/29

N2 - Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology - pressure and flow - as clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.

AB - Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology - pressure and flow - as clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.

KW - coronary flow

KW - coronary physiology

KW - ischemia

KW - PET perfusion imaging

KW - revascularization

UR - https://www.scopus.com/pages/publications/84886425343

U2 - 10.1016/j.jacc.2013.07.076

DO - 10.1016/j.jacc.2013.07.076

M3 - Review article

C2 - 23954338

AN - SCOPUS:84886425343

SN - 0735-1097

VL - 62

SP - 1639

EP - 1653

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 18

ER -

Gould KL, Johnson NP, Bateman TM, Beanlands RS, Bengel FM, Bober R et al. Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making. Journal of the American College of Cardiology. 2013 Oct 29;62(18):1639-1653. doi: 10.1016/j.jacc.2013.07.076

Anatomic versus physiologic assessment of coronary artery disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making

Abstract

Keywords

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