Abstract
A linear model for the membrane potential of a nerve ending associated with a sense-of-touch skin receptor is formulated and analyzed. Because the nerve has cytoplasmic extensions and is stimulated through a membrane strain mechanism, the model is a generalized cable equation with linear oblique boundary conditions (i.e. boundary conditions involving both time and space derivatives). The model is stimulated through a certain conductance parameter. We establish solutions for the problem and we consider a particular physiological question, both analytically and computationally, of determining conditions on parameters and stimulus which give threshold level potential values at a particular boundary point.
| Original language | English |
|---|---|
| Pages (from-to) | 1-45 |
| Number of pages | 45 |
| Journal | Mathematical Biosciences |
| Volume | 158 |
| Issue number | 1 |
| DOIs | |
| State | Published - Apr 1999 |
Keywords
- Cable equation
- Contraction map
- Green's function
- Oblique boundary condition
- Pacinian corpuscle
- Skin receptor
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