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Analysis of a model of membrane potential for a skin receptor

  • SUNY Buffalo

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A linear model for the membrane potential of a nerve ending associated with a sense-of-touch skin receptor is formulated and analyzed. Because the nerve has cytoplasmic extensions and is stimulated through a membrane strain mechanism, the model is a generalized cable equation with linear oblique boundary conditions (i.e. boundary conditions involving both time and space derivatives). The model is stimulated through a certain conductance parameter. We establish solutions for the problem and we consider a particular physiological question, both analytically and computationally, of determining conditions on parameters and stimulus which give threshold level potential values at a particular boundary point.

Original languageEnglish
Pages (from-to)1-45
Number of pages45
JournalMathematical Biosciences
Volume158
Issue number1
DOIs
StatePublished - Apr 1999

Keywords

  • Cable equation
  • Contraction map
  • Green's function
  • Oblique boundary condition
  • Pacinian corpuscle
  • Skin receptor

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