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An automated [15O]H2O production and injection system for PET imaging

  • Department of Veterans Affairs

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

A computer controlled [15O]H2O injection system has been designed for multiple bolus injections during PET cerebral blood flow studies. The system is housed in a lead safe, and radiation exposure to nearby personnel is low; we have measured rates of approx. 100 μSv/h (10 mR/h) during 2 min of [15O]H2O production and < 50 μSv/h (< 5 mR/h) after 3.7 GBq (100 mCi) has been produced. Reproducibility studies show that the injected activity varies with a coefficient of variation of 2-3%.

Original languageEnglish
Pages (from-to)241-249
Number of pages9
JournalNuclear Medicine and Biology
Volume22
Issue number2
DOIs
StatePublished - Feb 1995

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