Amyloid-β-related angiitis: A rare cause of recurrent transient neurological symptoms

Amy Amick; Jeff Joseph; Nicholas Silvestri; Magdy Selim

doi:10.1038/ncpneuro0769

Amyloid-β-related angiitis: A rare cause of recurrent transient neurological symptoms

Amy Amick
, Jeff Joseph
, Nicholas Silvestri
, Magdy Selim

Neurology

Beth Israel Deaconess Medical Center
University of Calgary

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Background: A 79-year-old woman presented with transient right-sided weakness. She subsequently developed further transient neurological signs and symptoms across a range of vascular territories. Diagnostic workup revealed no clear etiology. The patient developed a sudden, fatal intracerebral hemorrhage, and the diagnosis was only revealed at autopsy. Investigations: Neurological examination, head CT, brain MRI, fluid-attenuated inversion recovery imaging, magnetic resonance angiography, lumbar puncture, CT angiography, electroencephalography, and brain autopsy. Diagnosis: Amyloid-β-related angiitis. Management: The patient expired before treatment could be initiated. Immunosuppressants are recommended for future cases.

Original language	English
Pages (from-to)	279-283
Number of pages	5
Journal	Nature Clinical Practice Neurology
Volume	4
Issue number	5
DOIs	https://doi.org/10.1038/ncpneuro0769
State	Published - May 2008

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title = "Amyloid-β-related angiitis: A rare cause of recurrent transient neurological symptoms",

abstract = "Background: A 79-year-old woman presented with transient right-sided weakness. She subsequently developed further transient neurological signs and symptoms across a range of vascular territories. Diagnostic workup revealed no clear etiology. The patient developed a sudden, fatal intracerebral hemorrhage, and the diagnosis was only revealed at autopsy. Investigations: Neurological examination, head CT, brain MRI, fluid-attenuated inversion recovery imaging, magnetic resonance angiography, lumbar puncture, CT angiography, electroencephalography, and brain autopsy. Diagnosis: Amyloid-β-related angiitis. Management: The patient expired before treatment could be initiated. Immunosuppressants are recommended for future cases.",

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AU - Silvestri, Nicholas

AU - Selim, Magdy

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N2 - Background: A 79-year-old woman presented with transient right-sided weakness. She subsequently developed further transient neurological signs and symptoms across a range of vascular territories. Diagnostic workup revealed no clear etiology. The patient developed a sudden, fatal intracerebral hemorrhage, and the diagnosis was only revealed at autopsy. Investigations: Neurological examination, head CT, brain MRI, fluid-attenuated inversion recovery imaging, magnetic resonance angiography, lumbar puncture, CT angiography, electroencephalography, and brain autopsy. Diagnosis: Amyloid-β-related angiitis. Management: The patient expired before treatment could be initiated. Immunosuppressants are recommended for future cases.

AB - Background: A 79-year-old woman presented with transient right-sided weakness. She subsequently developed further transient neurological signs and symptoms across a range of vascular territories. Diagnostic workup revealed no clear etiology. The patient developed a sudden, fatal intracerebral hemorrhage, and the diagnosis was only revealed at autopsy. Investigations: Neurological examination, head CT, brain MRI, fluid-attenuated inversion recovery imaging, magnetic resonance angiography, lumbar puncture, CT angiography, electroencephalography, and brain autopsy. Diagnosis: Amyloid-β-related angiitis. Management: The patient expired before treatment could be initiated. Immunosuppressants are recommended for future cases.

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Amyloid-β-related angiitis: A rare cause of recurrent transient neurological symptoms

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