Amplifikatsiia uchastkov genoma v somaticheskikh kletkakh mlekopitaiushchikh, ustoǐchivykh k kolkhitsinu. Soobshchenie VII. Lokalizatsiia iskhodnoǐ i amplifitsirovannykh kopiǐ gena mdr v odnom i tom zhe segmente khromosomy 4 dzhungarskogo khomiachka.

O. I. Sokova; E. I. Siianova; A. V. Gudkov; B. P. Kopnin

Amplifikatsiia uchastkov genoma v somaticheskikh kletkakh mlekopitaiushchikh, ustoǐchivykh k kolkhitsinu. Soobshchenie VII. Lokalizatsiia iskhodnoǐ i amplifitsirovannykh kopiǐ gena mdr v odnom i tom zhe segmente khromosomy 4 dzhungarskogo khomiachka.

Translated title of the contribution: Amplification of regions of the genome in the somatic cells of mammals resistant to colchicine. VII. Localization of the initial and amplified copies of gene mdr in one and the same segment of chromosome 4 of the Djungarian hamster

O. I. Sokova
, E. I. Siianova
, A. V. Gudkov
, B. P. Kopnin

Roswell Park - Cell Stress and Biophysical Oncology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

By in situ hybridization technique, the mdr gene which is amplified during the development of multiple drug resistance was mapped in the 4q15--21 segment of normal Djungarian hamster chromosome 4. As was shown earlier, this chromosomal region is specific for the location of amplified mdr gene copies. These results, as well as some data obtained by other authors, suggest that recombinations of amplified DNAs occur preferentially in or near the sites bearing homologous sequences.

Translated title of the contribution	Amplification of regions of the genome in the somatic cells of mammals resistant to colchicine. VII. Localization of the initial and amplified copies of gene mdr in one and the same segment of chromosome 4 of the Djungarian hamster
Original language	Russian
Pages (from-to)	836-841
Number of pages	6
Journal	Genetika
Volume	24
Issue number	5
State	Published - May 1988

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@article{04065d78ef114445b30f44cf0c5e96bd,

title = "Amplifikatsiia uchastkov genoma v somaticheskikh kletkakh mlekopitaiushchikh, ustoǐchivykh k kolkhitsinu. Soobshchenie VII. Lokalizatsiia iskhodnoǐ i amplifitsirovannykh kopiǐ gena mdr v odnom i tom zhe segmente khromosomy 4 dzhungarskogo khomiachka.",

abstract = "By in situ hybridization technique, the mdr gene which is amplified during the development of multiple drug resistance was mapped in the 4q15--21 segment of normal Djungarian hamster chromosome 4. As was shown earlier, this chromosomal region is specific for the location of amplified mdr gene copies. These results, as well as some data obtained by other authors, suggest that recombinations of amplified DNAs occur preferentially in or near the sites bearing homologous sequences.",

author = "Sokova, \{O. I.\} and Siianova, \{E. I.\} and Gudkov, \{A. V.\} and Kopnin, \{B. P.\}",

year = "1988",

month = may,

language = "Russian",

volume = "24",

pages = "836--841",

journal = "Genetika",

issn = "0016-6758",

publisher = "Nauka",

number = "5",

}

Amplifikatsiia uchastkov genoma v somaticheskikh kletkakh mlekopitaiushchikh, ustoǐchivykh k kolkhitsinu. Soobshchenie VII. Lokalizatsiia iskhodnoǐ i amplifitsirovannykh kopiǐ gena mdr v odnom i tom zhe segmente khromosomy 4 dzhungarskogo khomiachka. / Sokova, O. I.; Siianova, E. I.; Gudkov, A. V. et al.
In: Genetika, Vol. 24, No. 5, 05.1988, p. 836-841.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Amplifikatsiia uchastkov genoma v somaticheskikh kletkakh mlekopitaiushchikh, ustoǐchivykh k kolkhitsinu. Soobshchenie VII. Lokalizatsiia iskhodnoǐ i amplifitsirovannykh kopiǐ gena mdr v odnom i tom zhe segmente khromosomy 4 dzhungarskogo khomiachka.

AU - Sokova, O. I.

AU - Siianova, E. I.

AU - Gudkov, A. V.

AU - Kopnin, B. P.

PY - 1988/5

Y1 - 1988/5

N2 - By in situ hybridization technique, the mdr gene which is amplified during the development of multiple drug resistance was mapped in the 4q15--21 segment of normal Djungarian hamster chromosome 4. As was shown earlier, this chromosomal region is specific for the location of amplified mdr gene copies. These results, as well as some data obtained by other authors, suggest that recombinations of amplified DNAs occur preferentially in or near the sites bearing homologous sequences.

AB - By in situ hybridization technique, the mdr gene which is amplified during the development of multiple drug resistance was mapped in the 4q15--21 segment of normal Djungarian hamster chromosome 4. As was shown earlier, this chromosomal region is specific for the location of amplified mdr gene copies. These results, as well as some data obtained by other authors, suggest that recombinations of amplified DNAs occur preferentially in or near the sites bearing homologous sequences.

UR - https://www.scopus.com/pages/publications/0024008815

M3 - Article

C2 - 3417136

AN - SCOPUS:0024008815

SN - 0016-6758

VL - 24

SP - 836

EP - 841

JO - Genetika

JF - Genetika

IS - 5

ER -

Amplifikatsiia uchastkov genoma v somaticheskikh kletkakh mlekopitaiushchikh, ustoǐchivykh k kolkhitsinu. Soobshchenie VII. Lokalizatsiia iskhodnoǐ i amplifitsirovannykh kopiǐ gena mdr v odnom i tom zhe segmente khromosomy 4 dzhungarskogo khomiachka.

Abstract

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