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Aminohydroxylation and Aminooxygenation of Alkenes

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Scopus citations

Abstract

The aminohydroxylation of alkenes provides β-amino alcohols (vicinal amino alcohols). A number of alkene aminohydroxylation protocols (and those of related reactions termed oxyamination and aminooxygenation), predominantly enabled by transition-metal catalysis, are described in this chapter, which focuses on literature published in the period 1996-2015. Cyclic and acyclic compounds containing vicinal amino alcohols and derivatives thereof can be prepared from alkenes with good regio- diastereo- and enantioselectivity.

Original languageEnglish
Title of host publicationScience of Synthesis
EditorsK. Muçiz
PublisherGeorg Thieme Verlag
Pages343-388
Number of pages46
Edition4
ISBN (Electronic)9783132403710
ISBN (Print)9783132012318
DOIs
StatePublished - 2018

Publication series

NameScience of Synthesis
Number4
Volume2017
ISSN (Print)2510-5469
ISSN (Electronic)2566-7297

Keywords

  • alkenes
  • aminohydroxylation
  • aminooxygenation
  • catalysis
  • copper catalysts
  • iron catalysts
  • manganese catalysts
  • osmium catalysts
  • oxyamination
  • palladium catalysts
  • rhodium catalysts
  • β-amino alcohols

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