Age-related hearing loss in BDF1 mice as evidenced by the brainstem auditory evoked potential1

M. W. Church; D. W. Shucard

doi:10.3109/00206098609078400

Age-related hearing loss in BDF₁ mice as evidenced by the brainstem auditory evoked potential¹

M. W. Church
, D. W. Shucard

Neurology

SUNY Buffalo

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Age-related hearing loss was studied in unanesthetized female BDF, mice using brainstem auditory evoked potential (BAEP) latency-intensity (L-I) profiles and BAEP thresholds. The mice were divided into 5 age-related groups: 3-4 months, 5.5-7 months, 9-10 months, 12 months and 18 months. Relative to the youngest group, BAEP threshold data indicated shifts in auditory sensitivity ranging from + 6 dB for the 5.5- to 7-month-old group to +71 dB for the 18-month-old group. The BAEP L-I profiles of older mice were consistent with recruitment-type sensorineural (cochlear) hearing losses. No evidence of retrocochlear involvement was observed.

Original language	English
Pages (from-to)	363-372
Number of pages	10
Journal	International Journal of Audiology
Volume	25
Issue number	6
DOIs	https://doi.org/10.3109/00206098609078400
State	Published - 1986

Keywords

Aging
Auditory brainstem response
Brainstem auditory evoked potential
Hearing loss
Presbycusis

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10.3109/00206098609078400

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title = "Age-related hearing loss in BDF1 mice as evidenced by the brainstem auditory evoked potential1",

abstract = "Age-related hearing loss was studied in unanesthetized female BDF, mice using brainstem auditory evoked potential (BAEP) latency-intensity (L-I) profiles and BAEP thresholds. The mice were divided into 5 age-related groups: 3-4 months, 5.5-7 months, 9-10 months, 12 months and 18 months. Relative to the youngest group, BAEP threshold data indicated shifts in auditory sensitivity ranging from + 6 dB for the 5.5- to 7-month-old group to +71 dB for the 18-month-old group. The BAEP L-I profiles of older mice were consistent with recruitment-type sensorineural (cochlear) hearing losses. No evidence of retrocochlear involvement was observed.",

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T1 - Age-related hearing loss in BDF1 mice as evidenced by the brainstem auditory evoked potential1

AU - Church, M. W.

AU - Shucard, D. W.

PY - 1986

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N2 - Age-related hearing loss was studied in unanesthetized female BDF, mice using brainstem auditory evoked potential (BAEP) latency-intensity (L-I) profiles and BAEP thresholds. The mice were divided into 5 age-related groups: 3-4 months, 5.5-7 months, 9-10 months, 12 months and 18 months. Relative to the youngest group, BAEP threshold data indicated shifts in auditory sensitivity ranging from + 6 dB for the 5.5- to 7-month-old group to +71 dB for the 18-month-old group. The BAEP L-I profiles of older mice were consistent with recruitment-type sensorineural (cochlear) hearing losses. No evidence of retrocochlear involvement was observed.

AB - Age-related hearing loss was studied in unanesthetized female BDF, mice using brainstem auditory evoked potential (BAEP) latency-intensity (L-I) profiles and BAEP thresholds. The mice were divided into 5 age-related groups: 3-4 months, 5.5-7 months, 9-10 months, 12 months and 18 months. Relative to the youngest group, BAEP threshold data indicated shifts in auditory sensitivity ranging from + 6 dB for the 5.5- to 7-month-old group to +71 dB for the 18-month-old group. The BAEP L-I profiles of older mice were consistent with recruitment-type sensorineural (cochlear) hearing losses. No evidence of retrocochlear involvement was observed.

KW - Aging

KW - Auditory brainstem response

KW - Brainstem auditory evoked potential

KW - Hearing loss

KW - Presbycusis

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EP - 372

JO - International Journal of Audiology

JF - International Journal of Audiology

IS - 6

ER -

Age-related hearing loss in BDF₁ mice as evidenced by the brainstem auditory evoked potential¹

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