Adult orbital langerhans cell histiocytosis with frontal bone involvement

Jason A. Sokol; Michael Kazim; Kara M. Kelly; George Lantos; Loh Shan Leung; Edward Baron

doi:10.1097/IOP.0b013e31819ac2d9

Adult orbital langerhans cell histiocytosis with frontal bone involvement

Jason A. Sokol
, Michael Kazim
, Kara M. Kelly
, George Lantos
, Loh Shan Leung
, Edward Baron

Pediatrics

Albert Einstein College of Medicine
Columbia University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A 28-year-old woman presented with a 2-week history of right upper eyelid swelling and intermittent frontal headaches. CT demonstrated an ill-defined superior right orbital mass with adjacent right frontal bone erosion and undeveloped frontal sinuses. The orbital biopsy revealed tissue strongly positive for CD1a and S100, diagnostic of Langerhans cell histiocytosis. The systemic workup was negative for multifocal lesions and for diabetes insipidus. In addition to subtotal resection, the patient was treated with a 6-month course of oral prednisone and intravenous vinblastine.

Original language	English
Pages (from-to)	157-158
Number of pages	2
Journal	Ophthalmic Plastic and Reconstructive Surgery
Volume	25
Issue number	2
DOIs	https://doi.org/10.1097/IOP.0b013e31819ac2d9
State	Published - Mar 2009

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title = "Adult orbital langerhans cell histiocytosis with frontal bone involvement",

abstract = "A 28-year-old woman presented with a 2-week history of right upper eyelid swelling and intermittent frontal headaches. CT demonstrated an ill-defined superior right orbital mass with adjacent right frontal bone erosion and undeveloped frontal sinuses. The orbital biopsy revealed tissue strongly positive for CD1a and S100, diagnostic of Langerhans cell histiocytosis. The systemic workup was negative for multifocal lesions and for diabetes insipidus. In addition to subtotal resection, the patient was treated with a 6-month course of oral prednisone and intravenous vinblastine.",

author = "Sokol, \{Jason A.\} and Michael Kazim and Kelly, \{Kara M.\} and George Lantos and Leung, \{Loh Shan\} and Edward Baron",

year = "2009",

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doi = "10.1097/IOP.0b013e31819ac2d9",

language = "English",

volume = "25",

pages = "157--158",

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T1 - Adult orbital langerhans cell histiocytosis with frontal bone involvement

AU - Sokol, Jason A.

AU - Kazim, Michael

AU - Kelly, Kara M.

AU - Lantos, George

AU - Leung, Loh Shan

AU - Baron, Edward

PY - 2009/3

Y1 - 2009/3

N2 - A 28-year-old woman presented with a 2-week history of right upper eyelid swelling and intermittent frontal headaches. CT demonstrated an ill-defined superior right orbital mass with adjacent right frontal bone erosion and undeveloped frontal sinuses. The orbital biopsy revealed tissue strongly positive for CD1a and S100, diagnostic of Langerhans cell histiocytosis. The systemic workup was negative for multifocal lesions and for diabetes insipidus. In addition to subtotal resection, the patient was treated with a 6-month course of oral prednisone and intravenous vinblastine.

AB - A 28-year-old woman presented with a 2-week history of right upper eyelid swelling and intermittent frontal headaches. CT demonstrated an ill-defined superior right orbital mass with adjacent right frontal bone erosion and undeveloped frontal sinuses. The orbital biopsy revealed tissue strongly positive for CD1a and S100, diagnostic of Langerhans cell histiocytosis. The systemic workup was negative for multifocal lesions and for diabetes insipidus. In addition to subtotal resection, the patient was treated with a 6-month course of oral prednisone and intravenous vinblastine.

UR - https://www.scopus.com/pages/publications/67049136612

U2 - 10.1097/IOP.0b013e31819ac2d9

DO - 10.1097/IOP.0b013e31819ac2d9

M3 - Article

C2 - 19300172

AN - SCOPUS:67049136612

SN - 0740-9303

VL - 25

SP - 157

EP - 158

JO - Ophthalmic Plastic and Reconstructive Surgery

JF - Ophthalmic Plastic and Reconstructive Surgery

IS - 2

ER -

Adult orbital langerhans cell histiocytosis with frontal bone involvement

Abstract

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