Accelerated exponential parameterization of T2 relaxation with model-driven low rank and sparsity priors (MORASA)

Purpose: This work is to develop a novel image reconstruction method from highly undersampled multichannel acquisition to reduce the scan time of exponential parameterization of T2 relaxation. Theory and Methods: On top of the low-rank and joint-sparsity constraints, we propose to exploit the linear predictability of the T2 exponential decay to further improve the reconstruction of the T2-weighted images from undersampled acquisitions. Specifically, the exact rank prior (i.e., number of non-zero singular values) is adopted to enforce the spatiotemporal low rankness, while the mixed L2–L1 norm of the wavelet coefficients is used to promote joint sparsity, and the Hankel low-rank approximation is used to impose linear predictability, which integrates the exponential behavior of the temporal signal into the reconstruction process. An efficient algorithm is adopted to solve the reconstruction problem, where corresponding nonlinear filtering operations are performed to enforce corresponding priors in an iterative manner. Results: Both simulated and in vivo datasets with multichannel acquisition were used to demonstrate the feasibility of the proposed method. Experimental results have shown that the newly introduced linear predictability prior improves the reconstruction quality of the T2-weighted images and benefits the subsequent T2 mapping by achieving high-speed, high-quality T2 mapping compared with the existing fast T2 mapping methods. Conclusion: This work proposes a novel fast T2 mapping method integrating the linear predictable property of the exponential decay into the reconstruction process. The proposed technique can effectively improve the reconstruction quality of the state-of-the-art fast imaging method exploiting image sparsity and spatiotemporal low rankness. Magn Reson Med 76:1865–1878, 2016.