A unique p52 NF-κB–ETS1 interaction ushers in a new paradigm of germinal center responses

Lee Ann Garrett-Sinha; Satrajit Sinha

doi:10.1038/s41590-025-02246-z

A unique p52 NF-κB–ETS1 interaction ushers in a new paradigm of germinal center responses

Biochemistry

Research output: Contribution to journal › Comment/debate

Abstract

A complex of the NF-κB family member p52 and the transcription factor ETS1 is required for B cell germinal center responses to T cell-dependent immunization and for IgE-dependent allergic responses.

Original language	English
Pages (from-to)	1434-1435
Number of pages	2
Journal	Nature Immunology
Volume	26
Issue number	9
DOIs	https://doi.org/10.1038/s41590-025-02246-z
State	Published - Sep 2025

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title = "A unique p52 NF-κB–ETS1 interaction ushers in a new paradigm of germinal center responses",

abstract = "A complex of the NF-κB family member p52 and the transcription factor ETS1 is required for B cell germinal center responses to T cell-dependent immunization and for IgE-dependent allergic responses.",

author = "Garrett-Sinha, \{Lee Ann\} and Satrajit Sinha",

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AU - Sinha, Satrajit

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PY - 2025/9

Y1 - 2025/9

N2 - A complex of the NF-κB family member p52 and the transcription factor ETS1 is required for B cell germinal center responses to T cell-dependent immunization and for IgE-dependent allergic responses.

AB - A complex of the NF-κB family member p52 and the transcription factor ETS1 is required for B cell germinal center responses to T cell-dependent immunization and for IgE-dependent allergic responses.

UR - https://www.scopus.com/pages/publications/105013314218

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DO - 10.1038/s41590-025-02246-z

M3 - Comment/debate

C2 - 40796661

AN - SCOPUS:105013314218

SN - 1529-2908

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JO - Nature Immunology

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A unique p52 NF-κB–ETS1 interaction ushers in a new paradigm of germinal center responses

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